Pharmaco-genomicsPharmacogenomic Pharmacological Effects and Adverse Drug Reactions

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Displaying entries 4676 - 4700 of 6330 in total

Drug	Interacting Gene/Enzyme	Allele name	Genotypes	Defining change(s)	Type(s)	Description	Details
							Clear
Citalopram	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*5	Not Available	1297C>T (rs56337013)	ADR Inferred	Poor drug metabolizer, increased risk of QT prolongation. For individual with two non-functional alleles, dose reduction or alternative drug recommended.	Details
Citalopram	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*6	Not Available	395G>A (rs72552267)	ADR Inferred	Poor drug metabolizer, increased risk of QT prolongation. For individual with two non-functional alleles, dose reduction or alternative drug recommended.	Details
Citalopram	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*7	Not Available	19294T>A (rs72558186)	ADR Inferred	Poor drug metabolizer, increased risk of QT prolongation. For individual with two non-functional alleles, dose reduction or alternative drug recommended.	Details
Citalopram	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*22	Not Available	557G>C (rs140278421) 991A>G	ADR Inferred	Poor drug metabolizer, increased risk of QT prolongation. For individual with two non-functional alleles, dose reduction or alternative drug recommended.	Details
Citalopram	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*24	Not Available	99C>T (rs17885098) 991A>G (rs3758581) 1004G>A (rs118203757) show all 4 …	ADR Inferred	Poor drug metabolizer, increased risk of QT prolongation. For individual with two non-functional alleles, dose reduction or alternative drug recommended.	Details
Citalopram	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*35	Not Available	12662A>G (rs12769205)	ADR Inferred	Poor drug metabolizer, increased risk of QT prolongation. For individual with two non-functional alleles, dose reduction or alternative drug recommended.	Details
Phenytoin	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*2A	Not Available	681G>A (rs4244285)	ADR Inferred	Poor drug metabolizer, risk of drug toxicity.	Details
Phenytoin	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*2B	Not Available	681G>A (rs4244285)	ADR Inferred	Poor drug metabolizer, risk of drug toxicity.	Details
Phenytoin	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*3	Not Available	636G>A (rs4986893)	ADR Inferred	Poor drug metabolizer, risk of drug toxicity.	Details
Phenytoin	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*4	Not Available	1A>G (rs28399504)	ADR Inferred	Poor drug metabolizer, risk of drug toxicity.	Details
Phenytoin	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*5	Not Available	1297C>T (rs56337013)	ADR Inferred	Poor drug metabolizer, risk of drug toxicity.	Details
Phenytoin	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*6	Not Available	395G>A (rs72552267)	ADR Inferred	Poor drug metabolizer, risk of drug toxicity.	Details
Phenytoin	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*7	Not Available	19294T>A (rs72558186)	ADR Inferred	Poor drug metabolizer, risk of drug toxicity.	Details
Phenytoin	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*22	Not Available	557G>C (rs140278421) 991A>G	ADR Inferred	Poor drug metabolizer, risk of drug toxicity.	Details
Phenytoin	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*24	Not Available	99C>T (rs17885098) 991A>G (rs3758581) 1004G>A (rs118203757) show all 4 …	ADR Inferred	Poor drug metabolizer, risk of drug toxicity.	Details
Phenytoin	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*35	Not Available	12662A>G (rs12769205)	ADR Inferred	Poor drug metabolizer, risk of drug toxicity.	Details
Phenytoin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*2	Not Available	430C>T (rs1799853)	ADR Inferred	Poor drug metabolizer, risk of drug toxicity. Consider lower dose.	Details
Phenytoin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*3	Not Available	1075A>C (rs1057910)	ADR Inferred	Poor drug metabolizer, risk of drug toxicity. Consider lower dose.	Details
Phenytoin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*4	Not Available	1076T>C (rs56165452)	ADR Inferred	Poor drug metabolizer, risk of drug toxicity. Consider lower dose.	Details
Phenytoin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*5	Not Available	1080C>G (rs28371686)	ADR Inferred	Poor drug metabolizer, risk of drug toxicity. Consider lower dose.	Details
Phenytoin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*8	Not Available	449G>A (rs7900194)	ADR Inferred	Poor drug metabolizer, risk of drug toxicity. Consider lower dose.	Details
Phenytoin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*11	Not Available	1003C>T (rs28371685)	ADR Inferred	Poor drug metabolizer, risk of drug toxicity. Consider lower dose.	Details
Phenytoin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*12	Not Available	1465C>T (rs9332239)	ADR Inferred	Poor drug metabolizer, risk of drug toxicity. Consider lower dose.	Details
Phenytoin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*13	Not Available	269T>C (rs72558187)	ADR Inferred	Poor drug metabolizer, risk of drug toxicity. Consider lower dose.	Details
Phenytoin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*14	Not Available	374G>A (rs72558189)	ADR Inferred	Poor drug metabolizer, risk of drug toxicity. Consider lower dose.	Details

Displaying entries 4676 - 4700 of 6330 in total

Pharmaco-genomicsPharmacogenomic Pharmacological Effects and Adverse Drug Reactions

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