Pharmaco-genomicsPharmacogenomic Pharmacological Effects and Adverse Drug Reactions

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Displaying entries 5076 - 5100 of 6330 in total

Drug	Interacting Gene/Enzyme	Allele name	Genotypes	Defining change(s)	Type(s)	Description	Details
							Clear
Trimipramine	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*4	Not Available	1A>G (rs28399504)	Effect Inferred	Poor drug metabolizer. For individual with two non-functional alleles, dose reduction recommended.	Details
Trimipramine	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*5	Not Available	1297C>T (rs56337013)	Effect Inferred	Poor drug metabolizer. For individual with two non-functional alleles, dose reduction recommended.	Details
Trimipramine	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*6	Not Available	395G>A (rs72552267)	Effect Inferred	Poor drug metabolizer. For individual with two non-functional alleles, dose reduction recommended.	Details
Trimipramine	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*7	Not Available	19294T>A (rs72558186)	Effect Inferred	Poor drug metabolizer. For individual with two non-functional alleles, dose reduction recommended.	Details
Trimipramine	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*22	Not Available	557G>C (rs140278421) 991A>G	Effect Inferred	Poor drug metabolizer. For individual with two non-functional alleles, dose reduction recommended.	Details
Trimipramine	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*24	Not Available	99C>T (rs17885098) 991A>G (rs3758581) 1004G>A (rs118203757) show all 4 …	Effect Inferred	Poor drug metabolizer. For individual with two non-functional alleles, dose reduction recommended.	Details
Trimipramine	Cytochrome P450 2C19 Gene symbol: CYP2C19 UniProt: P33261	CYP2C19*35	Not Available	12662A>G (rs12769205)	Effect Inferred	Poor drug metabolizer. For individual with two non-functional alleles, dose reduction recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*7	Not Available	2935A>C (rs5030867)	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*8	Not Available	1758G>T (rs5030865)	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*11	Not Available	883G>C (rs5030863)	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*12	Not Available	124G>A (rs5030862)	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*13	Not Available	CYP2D7/2D6 hybrid gene structure	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*14A	Not Available	1758G>A (rs5030865)	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*15	Not Available	137insT, 137_138insT	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*19	Not Available	2539_2542delAACT (rs72549353)	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*20	Not Available	1973_1974insG (rs72549354)	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*21	Not Available	2573insC	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*31	Not Available	-1770G>A -1584C>G -1235A>G show all 17 …	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*36	Not Available	100C>T (rs1065852) -1426C>T variable number of A’s in the region -1258 to -1237a show all 9 …	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*38	Not Available	2587_2590delGACT (rs72549351)	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*40	Not Available	1863_1864ins(TTT CGC CCC)2 (rs72549356)	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*42	Not Available	3259_3260insGT (rs72549346)	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*44	Not Available	2950G>C	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*47	Not Available	100C>T (rs1065852) -1426C>T -1235A>G show all 8 …	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*51	Not Available	-1584C>G -1235A>G -740C>T show all 9 …	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details

Displaying entries 5076 - 5100 of 6330 in total

Pharmaco-genomicsPharmacogenomic Pharmacological Effects and Adverse Drug Reactions

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