Pharmaco-genomicsPharmacogenomic Pharmacological Effects and Adverse Drug Reactions

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Displaying entries 5101 - 5125 of 6330 in total

Drug	Interacting Gene/Enzyme	Allele name	Genotypes	Defining change(s)	Type(s)	Description	Details
							Clear
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*56	Not Available	3201C>T (rs72549347)	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*57	Not Available	100C>T 310G>T 843T>G show all 10 …	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*62	Not Available	4044C>T	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*68A	Not Available	-1426C>T -1235A>G -1000G>A show all 6 …	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*68B	Not Available	Similar but not identical switch region compared to CYP2D668A. Found in tandem arrangement with CYP2D64.	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*69	Not Available	2988G>A (rs28371725) -1426C>T -1235A>G show all 17 …	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*92	Not Available	1995delC	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*100	Not Available	-1426C>T -1235A>G -1109C>T show all 15 …	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*101	Not Available	-1426C>T -1235A>G -1000G>A show all 14 …	Effect Inferred	Poor drug metabolizer. Lack of efficacy. For individual with two non-functional alleles, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*1XN	Not Available	Normal allele duplicated.	ADR Inferred	Ultra-rapid drug metabolizer. Risk of toxicity, alternative drug recommended.	Details
Codeine	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*2XN	Not Available	2850C>T (rs16947) 4180G>C (rs1135840) 1661G>C duplicated	ADR Inferred	Ultra-rapid drug metabolizer. Risk of toxicity, alternative drug recommended.	Details
Ondansetron	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*1XN	Not Available	Normal allele duplicated.	ADR Inferred	Ultra-rapid drug metabolizer. Risk of toxicity, alternative drug recommended.	Details
Ondansetron	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*2XN	Not Available	2850C>T (rs16947) 4180G>C (rs1135840) 1661G>C duplicated	ADR Inferred	Ultra-rapid drug metabolizer. Risk of toxicity, alternative drug recommended.	Details
Tropisetron	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*1XN	Not Available	Normal allele duplicated.	ADR Inferred	Ultra-rapid drug metabolizer. Risk of toxicity, alternative drug recommended.	Details
Tropisetron	Cytochrome P450 2D6 Gene symbol: CYP2D6 UniProt: P10635	CYP2D6*2XN	Not Available	2850C>T (rs16947) 4180G>C (rs1135840) 1661G>C duplicated	ADR Inferred	Ultra-rapid drug metabolizer. Risk of toxicity, alternative drug recommended.	Details
Warfarin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*4	Not Available	1076T>C (rs56165452)	Effect Inferred	Poor drug metabolizer, lower dose recommended.	Details
Warfarin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*5	Not Available	1080C>G (rs28371686)	Effect Inferred	Poor drug metabolizer, lower dose recommended.	Details
Warfarin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*8	Not Available	449G>A (rs7900194)	Effect Inferred	Poor drug metabolizer, lower dose recommended.	Details
Warfarin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*11	Not Available	1003C>T (rs28371685)	Effect Inferred	Poor drug metabolizer, lower dose recommended.	Details
Warfarin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*12	Not Available	1465C>T (rs9332239)	Effect Inferred	Poor drug metabolizer, lower dose recommended.	Details
Warfarin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*13	Not Available	269T>C (rs72558187)	Effect Inferred	Poor drug metabolizer, lower dose recommended.	Details
Warfarin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*14	Not Available	374G>A (rs72558189)	Effect Inferred	Poor drug metabolizer, lower dose recommended.	Details
Warfarin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*16	Not Available	895A>G (rs72558192)	Effect Inferred	Poor drug metabolizer, lower dose recommended.	Details
Warfarin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*18	Not Available	1075A>C 1190A>C 1425A>T	Effect Inferred	Poor drug metabolizer, lower dose recommended.	Details
Warfarin	Cytochrome P450 2C9 Gene symbol: CYP2C9 UniProt: P11712	CYP2C9*26	Not Available	389C>G	Effect Inferred	Poor drug metabolizer, lower dose recommended.	Details

Displaying entries 5101 - 5125 of 6330 in total

Pharmaco-genomicsPharmacogenomic Pharmacological Effects and Adverse Drug Reactions

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