NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
Details
- Name
- NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
- Synonyms
- 1.6.5.3
- NADH-ubiquinone oxidoreductase 24 kDa subunit
- Gene Name
- NDUFV2
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0010175|NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial MFFSAALRARAAGLTAHWGRHVRNLHKTVMQNGAGGALFVHRDTPENNPDTPFDFTPENY KRIEAIVKNYPEGHKAAAVLPVLDLAQRQNGWLPISAMNKVAEVLQVPPMRVYEVATFYT MYNRKPVGKYHIQVCTTTPCMLRNSDSILEAIQKKLGIKVGETTPDKLFTLIEVECLGAC VNAPMVQINDNYYEDLTAKDIEEIIDELKAGKIPKPGPRSGRFSCEPAGGLTSLTEPPKG PGFGVQAGL
- Number of residues
- 249
- Molecular Weight
- 27391.36
- Theoretical pI
- 8.21
- GO Classification
- Functions2 iron, 2 sulfur cluster binding / electron carrier activity / metal ion binding / NADH dehydrogenase (ubiquinone) activityProcessescardiac muscle tissue development / cellular metabolic process / mitochondrial electron transport, NADH to ubiquinone / nervous system development / respiratory electron transport chain / small molecule metabolic processComponentsmitochondrial inner membrane / mitochondrial respiratory chain complex I / mitochondrion / myelin sheath
- General Function
- Nadh dehydrogenase (ubiquinone) activity
- Specific Function
- Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
- Pfam Domain Function
- Complex1_24kDa (PF01257)
- Transmembrane Regions
- Not Available
- Cellular Location
- Mitochondrion inner membrane
- Gene sequence
>lcl|BSEQ0010176|NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (NDUFV2) ATGTTCTTCTCCGCGGCGCTCCGGGCCCGGGCGGCTGGCCTCACCGCCCACTGGGGAAGA CATGTAAGGAATTTGCATAAGACAGTTATGCAAAATGGAGCTGGAGGAGCTTTATTTGTG CACAGAGATACTCCTGAGAATAACCCTGATACTCCATTTGATTTCACACCAGAAAACTAT AAGAGGATAGAGGCAATTGTAAAAAACTATCCAGAAGGCCATAAAGCAGCAGCTGTTCTT CCAGTCCTGGATTTAGCCCAAAGGCAGAATGGGTGGTTGCCCATCTCTGCTATGAACAAG GTTGCAGAAGTTTTACAAGTACCTCCAATGAGAGTATATGAAGTAGCAACTTTTTATACA ATGTATAATCGAAAGCCAGTTGGAAAGTATCACATTCAGGTCTGCACTACTACACCCTGC ATGCTTCGAAACTCTGACAGCATACTGGAGGCCATTCAGAAAAAGCTTGGAATAAAGGTT GGGGAGACTACACCTGACAAACTTTTCACTCTTATAGAAGTGGAATGTTTAGGGGCCTGT GTGAACGCACCAATGGTTCAAATAAATGACAATTACTATGAGGATTTGACAGCTAAGGAT ATTGAAGAAATTATTGATGAGCTCAAGGCTGGCAAAATCCCAAAACCAGGGCCAAGGAGT GGACGCTTCTCTTGTGAGCCAGCTGGAGGTCTTACCTCTTTGACTGAACCACCCAAGGGA CCTGGATTTGGTGTACAAGCAGGCCTTTAA
- Chromosome Location
- 18
- Locus
- 18p11.31-p11.2
- External Identifiers
Resource Link UniProtKB ID P19404 UniProtKB Entry Name NDUV2_HUMAN GenBank Protein ID 188852 GenBank Gene ID M22538 GenAtlas ID NDUFV2 HGNC ID HGNC:7717 - General References
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