Radixin
Details
- Name
- Radixin
- Synonyms
- Not Available
- Gene Name
- RDX
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0009437|Radixin MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLK LNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPE TAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHR GMLREDSMMEYLKIAQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGF PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTI EVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIK AQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAE LAEFTAKIALLEEAKKKKEEEATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIP PTENEHDEHDENNAEASAELSNEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARD ETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM
- Number of residues
- 583
- Molecular Weight
- 68563.48
- Theoretical pI
- Not Available
- GO Classification
- Functionsactin binding / ATPase binding / poly(A) RNA binding / protein homodimerization activity / protein kinase A bindingProcessesactin filament capping / apical protein localization / cellular response to thyroid hormone stimulus / establishment of endothelial barrier / establishment of protein localization / establishment of protein localization to plasma membrane / microvillus assembly / negative regulation of adherens junction organization / negative regulation of cell size / negative regulation of GTPase activity / negative regulation of homotypic cell-cell adhesion / positive regulation of cell migration / positive regulation of cellular protein catabolic process / positive regulation of early endosome to late endosome transport / positive regulation of G1/S transition of mitotic cell cycle / positive regulation of gene expression / positive regulation of protein localization to early endosome / protein kinase A signaling / regulation of actin filament bundle assembly / regulation of cell shape / regulation of cell size / regulation of GTPase activity / regulation of organelle assembly / regulation of Rap protein signal transduction / regulation of ruffle assemblyComponentsapical plasma membrane / cell periphery / cleavage furrow / cortical actin cytoskeleton / extracellular exosome / extracellular space / extrinsic component of membrane / filopodium / focal adhesion / lamellipodium / microvillus / myelin sheath / plasma membrane / ruffle / stereocilium
- General Function
- Protein kinase a binding
- Specific Function
- Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane.
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cell membrane
- Gene sequence
>lcl|BSEQ0021875|Radixin (RDX) ATGCCGAAACCAATCAACGTAAGAGTAACTACAATGGATGCTGAGCTGGAATTTGCCATT CAGCCCAATACAACTGGCAAACAACTTTTTGACCAGGTGGTGAAAACAGTTGGTTTGCGT GAGGTCTGGTTTTTTGGGCTGCAGTATGTAGACAGCAAAGGTTATTCTACATGGCTTAAA CTAAATAAAAAGGTAACACAGCAGGATGTTAAAAAAGAGAATCCTTTACAGTTCAAGTTT AGAGCTAAATTCTTTCCTGAAGATGTTTCTGAGGAATTAATTCAAGAAATAACCCAGAGA CTCTTCTTCTTGCAAGTTAAAGAAGCCATCTTAAATGATGAGATATATTGCCCGCCAGAA ACTGCAGTTCTTTTGGCTTCCTATGCTGTCCAAGCCAAGTATGGAGATTACAATAAAGAG ATTCATAAGCCAGGCTACCTGGCTAATGATAGACTCCTACCCCAGCGTGTATTGGAACAA CACAAACTAACAAAAGAACAGTGGGAAGAAAGAATACAGAACTGGCATGAAGAACATAGA GGAATGTTAAGGGAGGATTCTATGATGGAATACCTGAAGATTGCACAAGATCTAGAAATG TATGGAGTCAACTATTTTGAAATAAAAAATAAAAAAGGAACTGAATTGTGGCTAGGTGTT GATGCTTTGGGTCTGAATATTTATGAGCATGACGACAAGTTAACACCTAAAATTGGTTTT CCCTGGAGTGAAATCAGAAATATTTCATTTAATGACAAAAAATTTGTTATAAAGCCAATC GACAAAAAGGCACCTGATTTTGTGTTTTATGCACCTCGTCTGAGAATCAATAAGCGGATT TTGGCCTTATGTATGGGAAACCATGAACTATACATGCGAAGAAGGAAGCCTGATACTATT GAAGTACAACAGATGAAGGCTCAGGCTAGGGAGGAGAAACATCAGAAGCAGTTGGAAAGG GCACAATTAGAGAATGAAAAGAAGAAAAGAGAAATAGCAGAAAAGGAAAAGGAAAGAATA GAACGTGAAAAGGAAGAGCTAATGGAACGTCTAAAACAAATTGAAGAGCAGACAATTAAA GCTCAGAAAGAACTAGAAGAACAGACTCGAAAAGCTCTAGAACTGGATCAAGAACGAAAA CGAGCAAAAGAAGAAGCAGAACGACTTGAAAAGGAGCGTCGAGCTGCTGAAGAGGCAAAG TCTGCCATAGCAAAACAAGCTGCCGACCAGATGAAGAATCAGGAGCAGCTAGCAGCAGAA CTTGCTGAATTCACTGCCAAGATTGCACTTCTAGAGGAAGCCAAGAAGAAAAAGGAAGAG GAAGCTACTGAGTGGCAACACAAAGCTTTTGCAGCCCAGGAAGACTTGGAAAAGACCAAA GAAGAGTTAAAAACTGTGATGTCTGCCCCCCCTCCACCTCCACCACCACCAGTCATTCCT CCAACAGAAAACGAACATGATGAACACGATGAGAATAATGCTGAAGCTAGTGCTGAATTA TCAAATGAAGGGGTAATGAACCATAGAAGCGAGGAAGAACGTGTAACCGAAACACAGAAA AATGAGCGTGTTAAGAAGCAACTTCAGGCATTAAGTTCAGAATTAGCCCAAGCCAGAGAT GAAACCAAGAAAACACAAAATGATGTTCTTCATGCTGAGAATGTTAAAGCAGGCCGTGAT AAGTACAAGACTCTGCGACAGATTCGACAAGGCAATACAAAGCAGCGTATCGATGAGTTT GAAGCAATGTGGGGACCCAAACTGTATGCATTGTTCCAGATGCGCTCTTGCCAAAGCAGC ATAAAGCAAATGTAA
- Chromosome Location
- 11
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P35241 UniProtKB Entry Name RADI_HUMAN HGNC ID HGNC:9944 - General References
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