Reaction: Doxepin to 2 products

N-demethylationMajor circulating metaboliteMetabolism of Doxepin

Doxepin is converted to Formaldehyde and N-desmethyldoxepin by Cytochrome P450 2D6, Cytochrome P450 2C9, Cytochrome P450 2C19 and 2 other enzymes.

Direction
Activity
active

What you can answer from here — as of April 17, 2019

5EnzymesEach linked to its target card
Listed above
3ReferencesThe literature this reaction is curated from
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Which other drugs are metabolised by Cytochrome P450 2D6, Cytochrome P450 2C9, and Cytochrome P450 2C19, and which of those pairings are clinically significant?

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