Reaction: E-10-Hydroxyamitriptyline to 1 product
N-demethylationMetabolism of Amitriptyline
E-10-Hydroxyamitriptyline is converted to E-10-Hydroxynortriptyline by Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9 and 1 other enzyme.
- Reaction
- Direction
- Not Available
- Activity
- active
What you can answer from here — as of December 09, 2017
4EnzymesEach linked to its target cardListed above
Which other drugs are metabolised by Cytochrome P450 1A2, Cytochrome P450 2C19, and Cytochrome P450 2C9, and which of those pairings are clinically significant?
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