Reaction: Selumetinib to 1 product
N-demethylationMetabolism of Selumetinib
Selumetinib is converted to M8 (N-desmethyl selumetinib) by Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2C8 and 2 other enzymes.
- Reaction
- Direction
- Activity
- active
What you can answer from here — as of April 20, 2020
5EnzymesEach linked to its target cardListed above
Which other drugs are metabolised by Cytochrome P450 2C19, Cytochrome P450 2C9, and Cytochrome P450 2C8, and which of those pairings are clinically significant?
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