Reaction: Azelastine to 1 product

N-demethylationMajor circulating metaboliteMetabolism of Azelastine

Azelastine is converted to Desmethylazelastine by Cytochrome P450 3A4, Cytochrome P450 2D6, Cytochrome P450 1A2 and 1 other enzyme.

Direction
Activity
active

What you can answer from here — as of August 29, 2019

4EnzymesEach linked to its target card
Listed above
2ReferencesThe literature this reaction is curated from
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Which other drugs are metabolised by Cytochrome P450 3A4, Cytochrome P450 2D6, and Cytochrome P450 1A2, and which of those pairings are clinically significant?

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