Reaction: Momelotinib to 1 product
oxidationMetabolism of Momelotinib
Momelotinib is converted to Momelotinib M21 metabolite by Cytochrome P450 3A4, Cytochrome P450 2C8, Cytochrome P450 2C19 and 2 other enzymes.
- Reaction
- Direction
- Activity
- active
- Comments
- The reaction is morpholine ring oxidation.
What you can answer from here — as of September 20, 2023
5EnzymesEach linked to its target cardListed above
Which other drugs are metabolised by Cytochrome P450 3A4, Cytochrome P450 2C8, and Cytochrome P450 2C19, and which of those pairings are clinically significant?
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