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Protein-arginine deiminase type-3
go.drugbank.com/bio_entities/BE0002315TargetHumansCatalyzes the deimination of arginine residues of proteins
Synonyms: Peptidylarginine deiminase III, Protein-arginine deiminase type IIIRibonuclease 3
go.drugbank.com/bio_entities/BE0020070TargetHumansRibonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. … Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies. Plays a role in growth homeostasis in response to autophagy in motor neurons (By similarity)
Synonyms: RNase III, Ribonuclease IIISecreted frizzled-related protein 4
go.drugbank.com/bio_entities/BE0009094TargetHumansThey have a role in regulating cell growth and differentiation in specific cell types (By similarity). SFRP4 plays a role in bone morphogenesis. … May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity).
Synonyms: Frizzled protein, human endometriumImmunoglobulin heavy variable 3-30
go.drugbank.com/bio_entities/BE0004312TargetHumansThe variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation … In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes
Synonyms: Ig heavy chain V-III region BUR, Ig heavy chain V-III region CAMImmunoglobulin kappa variable 3-20
go.drugbank.com/bio_entities/BE0000616TargetHumansThe variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation … In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes
Synonyms: Ig kappa chain V-III region B6, Ig kappa chain V-III region GOLSiroheme synthase
go.drugbank.com/bio_entities/BE0002522TargetSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.
Synonyms: Urogen III methylaseFe(3+)-pyochelin receptor
go.drugbank.com/bio_entities/BE0004170TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)High-affinity outer membrane receptor required for the transport of Fe(3+)-pyochelin.
Synonyms: Fe(III)-pyochelin receptorAquaporin-1
go.drugbank.com/bio_entities/BE0000880TargetTransporterHumansForms a water channel that facilitates the transport of water across cell membranes, playing a crucial role in water homeostasis in various tissues (PubMed:1373524, PubMed:23219802). … In vitro, it shows non-selective gated cation channel activity and may be permeable to cations like K(+) and Na(+) in vivo (PubMed:36949749, PubMed:8703053)
Synonyms: Urine water channelTissue factor
go.drugbank.com/bio_entities/BE0001178TargetHumansTF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade
Synonyms: Coagulation factor IIICytochrome b
go.drugbank.com/bio_entities/BE0004428TargetPlasmodium falciparumComponent of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.
Synonyms: Complex III subunit III, Complex III subunit 3