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Displaying results 91 - 100 of 6222 in total
  1. Target

    Calcium transporting ATPases

    go.drugbank.com/bio_entities/BE0010002
    TargetHumans

    Calcium/calmodulin-regulated and magnesium-dependent enzyme that catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell (PubMed:8530416). … Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis (PubMed:35358416).

    Polypeptides: Calcium-transporting ATPase type 2C member 1, Calcium-transporting ATPase type 2C member 2Synonyms: Calcium pump 1, Calcium pump 2
  2. Target

    Calcium release-activated calcium channel protein 1

    go.drugbank.com/bio_entities/BE0018211
    TargetHumans

    Pore-forming subunit of two major inward rectifying Ca(2+) channels at the plasma membrane: Ca(2+) release-activated Ca(2+) (CRAC) channels and arachidonate-regulated Ca(2+)-selective (ARC) channels (Probable) (PubMed:16645049, PubMed:16...

    Polypeptides: Calcium release-activated calcium channel protein 1Function: calcium channel activity
  3. Target

    Calcium-transporting ATPase

    go.drugbank.com/bio_entities/BE0009199
    TargetPlasmodium falciparum (isolate K1 / Thailand)

    This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium.

    Polypeptides: Calcium-transporting ATPaseSynonyms: Calcium pump
  4. Target

    Amorphous calcium phosphate

    go.drugbank.com/bio_entities/BE0008720
    TargetHumans

  5. Target

    Calcium-activated potassium channel

    go.drugbank.com/bio_entities/BE0004906
    TargetHumans

    calcium affinity for activation. … May decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations.

    Polypeptides: Calcium-activated potassium channel subunit alpha-1, Calcium-activated potassium channel subunit beta-1Synonyms: Calcium-activated potassium channel subunit beta, Calcium-activated potassium channel, subfamily M subunit alpha-1
  6. Target

    Voltage-dependent calcium channel

    go.drugbank.com/bio_entities/BE0004902
    TargetHumans

    The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel … The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel.

    Polypeptides: Voltage-dependent calcium channel gamma-1 subunit, Voltage-dependent calcium channel gamma-2 subunitSynonyms: Brain calcium channel I, Brain calcium channel II
  7. Target

    Calcium/manganese antiporter SLC30A10

    go.drugbank.com/bio_entities/BE0009899
    TransporterHumans

    Calcium:manganese antiporter of the plasma membrane mediating the efflux of intracellular manganese coupled to an active extracellular calcium exchange (PubMed:30755481).

    Polypeptides: Calcium/manganese antiporter SLC30A10Function: calcium
  8. Target

    Neuronal calcium sensor 1

    go.drugbank.com/bio_entities/BE0004557
    TargetHumans

    Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. … May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel (By similarity)

    Polypeptides: Neuronal calcium sensor 1Function: calcium ion binding
  9. Target

    Extracellular calcium-sensing receptor

    go.drugbank.com/bio_entities/BE0000509
    TargetHumans

    G protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis (PubMed:17555508, PubMed:19789209, PubMed:21566075 … Senses fluctuations in the circulating calcium concentration: activated by elevated circulating calcium, leading to decreased parathyroid hormone (PTH) secretion in parathyroid glands (By similarity).

    Polypeptides: Extracellular calcium-sensing receptorSynonyms: Parathyroid cell calcium-sensing receptor 1
  10. Target

    Sodium/calcium exchanger 1

    go.drugbank.com/bio_entities/BE0000986
    TargetTransporterHumans

    Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes (PubMed:11241183, PubMed:13...

    Polypeptides: Sodium/calcium exchanger 1