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Displaying results 91 - 100 of 10000 in total
  1. Drug

    Pralatrexate

    go.drugbank.com/drugs/DB06813
    ApprovedInvestigational

    [A246693] Pralatrexate is designed to have a higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and is upregulated by oncogenes. … [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell lung cancer, breast cancer, and bladder cancer.[A246678]

    Synonyms: 10-Propargyl-10-deazaaminopterin, N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acidCategories: Heterocyclic Compounds, 2-Ring, Antineoplastic and Immunomodulating Agents
  2. Drug

    Doxycycline

    go.drugbank.com/drugs/DB00254
    ApprovedInvestigationalVet approved

    [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.[A251730] … Doxycycline is a broad-spectrum antibiotic synthetically derived from [oxytetracycline].[L42880] It is a second-generation tetracycline that was first discovered in 1967.

    Mixtures: BenzoDox 30 Kit, BenzoDox 60 KitCategories: Alimentary Tract and Metabolism, Antiinfectives and Antiseptics for Local Oral Treatment
  3. Drug

    Metronidazole

    go.drugbank.com/drugs/DB00916
    ApprovedInvestigational

    Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. … It is available in capsule form, tablet form, and topical form, and suppository preparations for the treatment of various infections.

    Synonyms: 1-(2-hydroxy-1-ethyl)-2-methyl-5-nitroimidazole, 2-methyl-5-nitroimidazole-1-ethanolInternational brands: Tricowas B
  4. Drug

    Flavin adenine dinucleotide

    go.drugbank.com/drugs/DB03147
    Approved

    A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase.

    Categories: Enzymes and Coenzymes, Nucleic Acids, Nucleotides, and NucleosidesSynonyms: Adenosine 5'-(trihydrogen pyrophosphate), 5'-5'-ester with riboflavine, Riboflavin 5'-(trihydrogen diphosphate), 5'-5'-ester with adenosine
  5. Drug

    Dienogest

    go.drugbank.com/drugs/DB09123
    ApprovedInvestigational

    It is a derivative of 19-nortestosterone and has antiandrogenic properties. … It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not available in the US by itself.

    Synonyms: 17-alpha-Cyanomethyl-17-beta-hydroxy-estra-4,9(10)-dien-3-one, 17alpha-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrileMixtures: VELBIENNE® 10, Velbienne 1 mg/2 mg Filmtabletten
  6. Drug

    Adenosine phosphate

    go.drugbank.com/drugs/DB00131
    ApprovedInvestigationalNutraceuticalWithdrawn

    Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. … Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.[L43937]

    Synonyms: 5'-AMP, Adenosine-5'PInternational brands: My-B-Den
  7. Drug

    Azacitidine

    go.drugbank.com/drugs/DB00928
    ApprovedInvestigational

    Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity. … As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and inhibiting protein and DNA synthesis.

    Synonyms: 4-amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one, 5 AzacitidineCategories: Heterocyclic Compounds, 1-Ring, Antineoplastic and Immunomodulating Agents
  8. Drug

    9-(2-carboxyethyl)-10-methylanthracene endoperoxide

    go.drugbank.com/drugs/DB08332
    Experimental

    Synonyms: 9-(2-carboxyethyl)-10-methylanthracene endoperoxide, [2'-CARBOXYLETHYL]-10-METHYL-ANTHRACENE ENDOPEROXIDE
  9. Drug

    Vinorelbine

    go.drugbank.com/drugs/DB00361
    ApprovedInvestigational

    It was initially approved in the USA in 1990's for the treatment of NSCLC [L2010]. It is a third-generation vinca alkaloid. … Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) [L1998].

    Categories: Antineoplastic and Immunomodulating Agents, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: 5'-Noranhydrovinblastine
  10. Drug

    (10R)-10-formyl-5,8,10-trideazafolic acid

    go.drugbank.com/drugs/DB04264
    Experimental

    Synonyms: (10R)-10-formyl-5,8,10-trideazafolic acid