Search

Displaying results 91 - 100 of 313 in total
  1. Target

    CMV DNA Terminase Complex

    go.drugbank.com/bio_entities/BE0010221
    TargetHuman Cytomegalovirus

    Forms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. … Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.

  2. Indication

    Primary Immune Complex Mediated Membranoproliferative Glomerulonephritis

    go.drugbank.com/conditions/DBCOND0173486
    Drugs: Pegcetacoplan
    Synonyms: Primary Immune Complex Mediated Membranoproliferative Glomerulonephritis
  3. Target

    Diamine oxidase [copper-containing]

    go.drugbank.com/bio_entities/BE0004667
    EnzymePig

    Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia (PubMed:1457410, PubMed:8144586). Its preferred substrates in vitro are the diamines hi...

    Polypeptides: Diamine oxidase [copper-containing]Synonyms: Amine oxidase copper domain-containing protein 1, Amiloride-sensitive amine oxidase [copper-containing]
  4. Target

    Diamine oxidase [copper-containing]

    go.drugbank.com/bio_entities/BE0000351
    TargetEnzymeHumans

    Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia (PubMed:12072962, PubMed:19764817, PubMed:239684, PubMed:8144586). Its preferred substr...

    Polypeptides: Diamine oxidase [copper-containing]Synonyms: Amine oxidase copper domain-containing protein 1
  5. Target

    Copper transport protein ATOX1

    go.drugbank.com/bio_entities/BE0002833
    TargetCarrierHumans

    Multifunctional copper-sensing protein that operates both as a cytosolic copper chaperone and as a copper-dependent transcription factor. … In the cytosol, transfers copper to the copper-transporting ATPase ATP7A at the trans-Golgi network, which is required for activation of secretory copper enzymes including lysyl oxidase (LOX) and SOD3.

    Polypeptides: Copper transport protein ATOX1
  6. Target

    Copper-transporting ATPase 1

    go.drugbank.com/bio_entities/BE0003666
    TransporterHumans

    ATP-driven copper (Cu(+)) ion pump that plays an important role in intracellular copper ion homeostasis (PubMed:10419525, PubMed:11092760, PubMed:28389643). … In the melanosomes of pigmented cells, provides copper cofactor to TYR to form an active TYR holoenzyme for melanin biosynthesis (By similarity)

    Polypeptides: Copper-transporting ATPase 1Synonyms: Copper pump 1
  7. Drug

    Pixofisiran

    go.drugbank.com/drugs/DB17294
    Experimental

    Synonyms: Rna, (a-g-a-a-g-u-u-g-g-c-a-u-g-g-u-a-g-c-c-c-u-u-g-g-g), complex with rna (c-c-c-a-a-g-g-g-c-u-a-c-c-a-u-g-c-c-a-a-c-u-u-c-u) (1:1)
  8. Target

    Proteasome activator complex subunit 1

    go.drugbank.com/bio_entities/BE0008976
    TargetHumans

    The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome

    Polypeptides: Proteasome activator complex subunit 1Synonyms: 11S regulator complex subunit alpha
  9. Target

    MHC class II protein complex

    go.drugbank.com/bio_entities/BE0011001
    TargetHumans

  10. Indication

    Tuberous Sclerosis Complex with Subependymal Giant Cell Astrocytoma

    go.drugbank.com/conditions/DBCOND0025535
    Drugs: Everolimus
    Synonyms: Tuberous Sclerosis Complex with Subependymal Giant Cell Astrocytoma