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Bemotrizinol
go.drugbank.com/drugs/DB11206ApprovedBemotrizinol, or bis-ethylhexyloxyphenol methoxyphenyl triazine, is an organic UV filter found in over-the-counter sunscreen products. It primarily absorbs UV-A rays. … Bemotrizinol is commonly marketed as Tinosorb S and Escalol S.
Mixtures: Nourishing Day Cream CRème De Jour Nourrissante SPF 15 Fps 15, Refreshing Day Cream CRème De Jour Rafraîchissante SPF 15 Fps 15Categories: Heterocyclic Compounds, 1-RingSirolimus
go.drugbank.com/drugs/DB00877ApprovedInvestigationalextensively investigated as an immunosuppressive and antitumour agent. … [A242412] In May 2015, the FDA approved sirolimus for the treatment of patients with lymphangioleiomyomatosis.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: LIKMUN-E, P-HYSPLANPalbociclib
go.drugbank.com/drugs/DB09073ApprovedInvestigationalIt is a second generation cyclin-dependent kinase inhibitor[A176798] selected from a group of pyridopyrimidine compounds due to its favorable physical and pharmaceutical properties. … Palbociclib is a piperazine pyridopyrimidine[A176792] that acts in the cell cycle machinery.
Mixtures: REAMPLA®, REAMPLA®Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexCertolizumab pegol
go.drugbank.com/drugs/DB08904ApprovedInvestigational[A176585] It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 kDa polyethylene glycol moiety replacing the Fc antibody region. … [A176606] Certolizumab does not require glycosylation for active function and hence, its production is significantly more affordable when compared to other existing TNF-alpha therapies as it can be
Products: CIMZIA®, CIMZIA 200MG FERGlycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approved[A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of peptic ulcers. … [L33105] Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and is considered to have a wider therapeutic window than [tiotropium].
Mixtures: TRIMBOW PRESSURISED INHALATION SOLUTION 100/6/12.5 μg PER ACTUATION, TRİMBOW 87/5/9 MCG AEROSOL İNHALASYON ÇÖZELTİSİ, 120 DOZCategories: MATE 1 Substrates, Cytochrome P-450 SubstratesCarbidopa
go.drugbank.com/drugs/DB00190ApprovedInvestigationalAn individual formulation containing solely carbidopa was generated to treat nausea in patients where the combination therapy [levodopa]/carbidopa is not efficient reducing nausea. … Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate.
Synonyms: L-3-(3,4-dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid, L-α-methyldopahydrazineMixtures: CARBIDOPA X 25 MG Y LEVODOPA X 250 MG, CARBIDOPA X 25 MG Y LEVODOPA X 250 MGMetoprolol
go.drugbank.com/drugs/DB00264ApprovedInvestigationalMetoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release. … [A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.[L5527]
Synonyms: 1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-olMixtures: METOPROLOL HCT S 100/12.5, METOPROLOL HCT S 100/12.5Loperamide
go.drugbank.com/drugs/DB00836ApprovedInvestigationalLoperamide is an anti-diarrheal agent that is available as an over-the-counter product for treating diarrhea.[L42785] The drug was first synthesized in 1969 and used medically in 1976. … [A251610] Loperamide has a chemical structure that is similar to diphenoxylate and haloperidol;[A6249] however, loperamide works on mu (μ)-opioid receptors to mediate its pharmacological actions.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: A D, Imodium A-DGeneralized tonic-clonic Seizures
go.drugbank.com/conditions/DBCOND0050096Synonyms: Grand mal, Grand mal fitMetocurine iodide
go.drugbank.com/drugs/DB00416ApprovedWithdrawnIt is used as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy Metocurine iodide has a moderate risk of inducing histamine … Metocurine iodide can be used most advantageously if muscle twitch response to peripheral nerve stimulation is monitored to assess degree of muscle relaxation.
Categories: Heterocyclic Compounds, 2-Ring