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Putative hydrolase DDAH2
go.drugbank.com/bio_entities/BE0000608TargetHumansPutative hydrolase with unknown substrate (Probable). Does not hydrolyze N(G),N(G)-dimethyl-L-arginine (ADMA) which acts as an inhibitor of NOS (PubMed:21493890, PubMed:37296100). In endothelial cells, induces expression of vascular endo...
Synonyms: S-phase proteinSuccinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
go.drugbank.com/bio_entities/BE0002256TargetEnzymeHumansKey enzyme for ketone body catabolism. Catalyzes the first, rate-limiting step of ketone body utilization in extrahepatic tissues, by transferring coenzyme A (CoA) from a donor thiolester species (succinyl-CoA) to an acceptor carboxylate...
Synonyms: SCOT-sPemetrexed
go.drugbank.com/drugs/DB00642ApprovedInvestigationalPemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. … Pemetrexed was first approved by the FDA in February 4, 2004.[A253907]
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: TEC PRED, PEMETREXED 500 MG POLVO LIOFILIZADO PARA SOLUCIÓN DE INFUSIÓN.Eucalyptol
go.drugbank.com/drugs/DB03852ApprovedInvestigationalNutraceuticalEucalyptol is naturally produced cyclic ether and monoterpenoid. Eucalyptol is an ingredient in many brands of mouthwash and cough suppressant. … Eucalyptol is an effective treatment for nonpurulent rhinosinusitis. Eucalyptol reduces inflammation and pain when applied topically. It kills leukaemia cells in vitro.
Mixtures: Aurora Blue Mint, Aurora Fresh BurstCategories: Compounds used in a research, industrial, or household settingTozasertib
go.drugbank.com/drugs/DB19675InvestigationalTozasertib is under investigation in clinical trial NCT02532868 (A VX-680 (an Aurora Kinase Inhibitor) Study in Patients With Advanced Cancer (0457-002)). … Tozasertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Tozasertib is a serine/threonine kinase inhibitor.
Categories: Heterocyclic Compounds, 1-RingSodium chloride
go.drugbank.com/drugs/DB09153ApprovedInvestigationalVet approvedSodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed on the World Health Organization Model List of Essential Medicines. … Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions.
Mixtures: B S S STERILE IRRIGATING SOLUTION, D-5-SProducts: CLORURO DE SODIO DE 2 MEQ/ML SOLUCIÓN INYECTABLE, BERKO-FIZ % 0,9 NAZAL ÇÖZELTI IÇEREN TEK KULLANIMLIK FLAKON, 5 ADETTick-Borne Encephalitis, European
go.drugbank.com/conditions/DBCOND0144103Synonyms: Tick-Borne Encephalitis, EuropeanDextropropoxyphene
go.drugbank.com/drugs/DB00647ApprovedIllicitWithdrawnDue to the risk of cardiac arrhythmias and overdose, possibly leading to death, dextropropoxyphene has been withdrawn from the market in Europe and the United States. … The drug is often referred to as the general form, "propoxyphene", however only the dextro-isomer (dextropropoxyphene) has any analgesic effect.
Mixtures: Darvocet-N 50, Darvocet-N 100Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesKynurenine--oxoglutarate transaminase 1
go.drugbank.com/bio_entities/BE0000273TargetEnzymeHumansCatalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (PubMed:7883047)
Synonyms: Cysteine-S-conjugate beta-lyaseFunction: cysteine-S-conjugate beta-lyase activityHematopoietic prostaglandin D synthase
go.drugbank.com/bio_entities/BE0001167TargetHumansBifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide rang...
Synonyms: Glutathione S-transferase