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Bivalirudin
go.drugbank.com/drugs/DB00006ApprovedInvestigationalBivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin.
Products: ANGIOMAX® POLVO LIOFILIZADO PARA RECONSTRUIR A SOLUCIÓN INYECTABLE (50MG/ML), OBIVADIN 250 MG IV ENJEKSIYON/INFÜZYON IÇIN LIYOFILIZE TOZ, 10 ADETMometasone furoate
go.drugbank.com/drugs/DB14512ApprovedInvestigationalVet approvedMometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different indications[FDA Label][F4292,F4295]. … It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than many other corticosteroids as well[A176906].
Mixtures: M-FURO FA %0.1 + %2 KREM, 30 G, MORFEX 5/100 MCG INHALASYON IÇIN ÖLÇÜLÜ DOZLU AEROSOL ,120 DOZCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProcaine
go.drugbank.com/drugs/DB00721ApprovedInvestigationalVet approvedA local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. … Procaine has also been investigated as an oral entry inhibitor in treatment-experienced HIV patients [L1215].
Synonyms: 2-Diethylaminoethyl p-aminobenzoate, β-(diethylamino)ethyl 4-aminobenzoateProducts: NTCAIN 100 MG/10 ML IM AMPUL, 100 ADET, Novocain 20 mg/mlSoybean oil
go.drugbank.com/drugs/DB09422ApprovedInvestigationalIt is a complex mixture of triglycerides where per 100 g, soybean oil has 16 g of saturated fat, 23 g of monounsaturated fat, and 58 g of polyunsaturated fat. … Derived from soybeans, soybean oil is a common vegetable oil and a source of polyunsaturated and saturated fatty acids.
Mixtures: SMOFlipid 200 mg/ml Emulsion zur Infusion, LIPOFUNDIN MCT/LCT %20 VIT E INFUZYON ICIN YAG EMULSUYONU, 100 MLProducts: INTRALIPID %20 100 ML YAG EMULSIYONU, CELEPID® 10%Papaverine
go.drugbank.com/drugs/DB01113ApprovedInvestigationalIt is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. … An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions.
Categories: Heterocyclic Compounds, 2-RingProducts: PAPAVERIN HIDROKLORUR 0.05 G/2 ML BIOSEL AMPUL, 100 ADET, PAPAVERIN HIDROKLORUR 0.06 G/2 ML BIOSEL AMPUL, 100 ADETDexibuprofen
go.drugbank.com/drugs/DB09213ApprovedWithdrawnDexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. … It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer.
Mixtures: TAFLAX® GRIP, TAFLAX®FORTE TABLETAS RECUBIERTASCategories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesDoxorubicin
go.drugbank.com/drugs/DB00997ApprovedInvestigationalDoxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970. … [A257614] Thanks to its efficacy and broad effect, doxorubicin was approved by the FDA in 1974 to treat a variety of cancer, including but not limited to breast, lung, gastric, ovarian, thyroid, non-Hodgkin
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic IndexSynonyms: (1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside, (8S-cis)-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedioneNiacin
go.drugbank.com/drugs/DB00627ApprovedInvestigationalNutraceuticalNiacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.
Mixtures: Niacin 500 Mg and Inositol, OB Complete 400Categories: Vitamin B Complex, Cytochrome P-450 CYP2D6 InhibitorsFlupentixol
go.drugbank.com/drugs/DB00875ApprovedInvestigationalWithdrawnFlupentixol is an antipsychotic drug of the thioxanthene group. It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. … Flupentixol decanoate is one of the active ingredients found in injectable drug formulations: it is produced by esterification of cis(Z)‐flupentixol with decanoic acid.
Mixtures: DORMIR TABLET, 20 ADETCategories: P-glycoprotein inhibitors, Heterocyclic Compounds, 1-RingGuaifenesin
go.drugbank.com/drugs/DB00874ApprovedInvestigationalVet approvedAfter the negotiation between FDA and major manufacturers, a voluntary transition of labels for not using guaifenesin in children under the age of 4 years was endorsed by FDA in 2008 [F4525]. … Regardless, on March 1, 2007, the FDA received a petition asking the FDA to notify the public that some antitussives, expectorants, decongestants, antihistamines, and cough/cold combinations are not known
Mixtures: BROKSIN 6.66 MG/5 ML+100 MG/5 ML SURUP, 150 ML, BİCANA 1,5 MG/5 ML + 66,5 MG/5 ML ŞURUP, 100 MLInternational brands: Duratuss G