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Displaying results 1021 - 1030 of 3387 in total
  1. Target

    Tumor necrosis factor receptor superfamily member 16

    go.drugbank.com/bio_entities/BE0010540
    TargetHumans

    Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. … Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF (PubMed:24908487).

    Polypeptides: Tumor necrosis factor receptor superfamily member 16Synonyms: NGF receptor, Low affinity neurotrophin receptor p75NTR
  2. Target

    Antiviral innate immune response receptor RIG-I

    go.drugbank.com/bio_entities/BE0012418
    TargetHumans

    Innate immune receptor that senses cytoplasmic viral nucleic acids and activates a downstream signaling cascade leading to the production of type I interferons and pro-inflammatory cytokines (PubMed:15208624

    Polypeptides: Antiviral innate immune response receptor RIG-ISynonyms: RIG-I-like receptor 1
  3. Target

    Tumor necrosis factor receptor superfamily member 13C

    go.drugbank.com/bio_entities/BE0018598
    TargetHumans

    B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response

    Polypeptides: Tumor necrosis factor receptor superfamily member 13CSynonyms: BAFF receptor, BLyS receptor 3
  4. Target

    Tumor necrosis factor receptor superfamily member 12A

    go.drugbank.com/bio_entities/BE0020009
    TargetHumans

    Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins

    Polypeptides: Tumor necrosis factor receptor superfamily member 12ASynonyms: Tweak-receptor
  5. Target

    Acetylcholine receptor subunit alpha-type acr-16

    go.drugbank.com/bio_entities/BE0027703
    TargetCaenorhabditis elegans

    A subunit of the levamisole-insensitive nicotinic receptor.

    Polypeptides: Acetylcholine receptor subunit alpha-type acr-16
  6. Drug

    Phosphatidyl serine

    go.drugbank.com/drugs/DB00144
    ApprovedNutraceutical

    PS has been shown to slow cognitive decline in animal models. … PS has been investigated in a small number of double-blind placebo trials and has been shown to increase memory performance in the elderly.

    Synonyms: PSInternational brands: LifeExtension PS Caps
  7. Drug

    MF-300

    go.drugbank.com/drugs/DB32060
    Investigational

    As a potential candidate for the treatment of sarcopenia, it has undergone phase 1 studies to evaluate safety, tolerability, and PK/PD characteristics.[A275368,L54983]

  8. Drug

    Cladribine

    go.drugbank.com/drugs/DB00242
    ApprovedInvestigational

    Cladribine is a purine analogue or a chlorinated derivative of adenine that causes apoptosis of B and T lymphocytes. Cladribine was first approved in the United States in 1993 initially as a treatment for a number of hematological malign...

    Categories: P-glycoprotein substrates
  9. Drug

    Altropane

    go.drugbank.com/drugs/DB04947
    Investigational

    Boston Life Sciences (BLS) is developing Altropane as a potential radio-imaging agent to be used with single photon emission tomography (SPECT), for the early diagnosis of Parkinson's disease (PD) and

  10. Drug

    Radotinib

    go.drugbank.com/drugs/DB12323
    Investigational

    Radotinib is under investigation for the treatment of Leukemia, Myelogenous, Chronic, BCR-ABL Positive.