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Displaying results 1021 - 1030 of 10000 in total
  1. Target

    ATP synthase F(0) complex subunit a

    go.drugbank.com/bio_entities/BE0009014
    TargetHumans

    These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk (PubMed:37244256). … ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256).

    Polypeptides: ATP synthase F(0) complex subunit aSynonyms: Proton-conducting channel, ATP synthase F(0) complex subunit a
  2. Target

    V-type proton ATPase catalytic subunit A

    go.drugbank.com/bio_entities/BE0009200
    TargetPlasmodium falciparum (isolate 3D7)

    Catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates

    Polypeptides: V-type proton ATPase catalytic subunit ASynonyms: V-ATPase subunit A
  3. Indication

    HLA-A*0201 Positive Cells Present

    go.drugbank.com/conditions/DBCOND0075175
    Drugs: Afamitresgene autoleucel · Tebentafusp
    Synonyms: HLA-A*0201 Positive Cells Present
  4. Indication

    Previously treated with a BRAF inhibitor

    go.drugbank.com/conditions/DBCOND0164673
    Drugs: Lifileucel
    Synonyms: Previously treated with a BRAF inhibitor
  5. Indication

    Perioperative Bleeding caused by Hemophilia A

    go.drugbank.com/conditions/DBCOND0089513
    Drugs: Anti-inhibitor coagulant complex
    Synonyms: Perioperative Bleeding caused by Hemophilia A
  6. Indication

    Congenital factor XIII A-subunit deficiency

    go.drugbank.com/conditions/DBCOND0023738
    Drugs: Catridecacog
    Synonyms: Congenital factor XIII A-subunit deficiency
  7. Drug

    Daunorubicin

    go.drugbank.com/drugs/DB00694
    ApprovedInvestigational

    A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: (8S-cis)-8-acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione, Leukaemomycin C
  8. Drug

    Secnidazole

    go.drugbank.com/drugs/DB12834
    ApprovedInvestigational

    Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. … It is structurally related to other 5-nitroimidazoles, including [DB00916] and [DB00911], but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class

    Synonyms: 1-(2-methyl-5-nitro-1H-imidazol-1-yl) propan-2­ ol, 1-(2­ hydroxypropyl)-2-methyl-5-nitroimidazoleMixtures: KADMIZOL®-F, GYNFLU® D TABLETAS
  9. Drug

    Rhubarb

    go.drugbank.com/drugs/DB10651
    Approved

    Rhubarb allergenic extract is used in allergenic testing.

    Mixtures: Vita-lax, Lax-easeCategories: Non-Standardized Food Allergenic Extract, Non-Standardized Plant Allergenic Extract
  10. Drug

    Vardenafil

    go.drugbank.com/drugs/DB00862
    Approved

    [A258313] The use of vardenafil as a monotherapy for the treatment of pulmonary arterial hypertension has also been evaluated.[A258308] … Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: Vardenafil 1 A Pharma 5 mg - Filmtabletten, Vardenafil 1 A Pharma 10 mg - Filmtabletten