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Bicisate
go.drugbank.com/drugs/DB11164Approved[A32374] The complex of bicisate and technetium Tc99m as a kit was developed by Lantheus Medcl and FDA-approved on November 23, 1994.[L2029] … Bicisate, also known as ethyl cysteinate dimer (ECD), is a N,N'-1,2-ethylene-di-yl-bis-L-cysteinate diethyl ester.
Sparfloxacin
go.drugbank.com/drugs/DB01208ApprovedWithdrawnDNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, deactivation, and transcription. … Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase.
Pariglasgene brecaparvovec
go.drugbank.com/drugs/DB16801Approved[L64050] The FDA granted pariglasgene brecaparvovec-opnr accelerated approval on August 19, 2026, making it the first approved treatment for glycogen storage disease type Ia. … [L64050,L64051] It is administered as a single, one-time intravenous infusion.
Talimogene laherparepvec
go.drugbank.com/drugs/DB13896ApprovedInvestigationalIt was approved by the FDA in 2015 under the market name Imlygic. In general, talimogene laherparepvec has been modified so that it can infect and multiply inside melanoma cells [L2221]. … It is a genetically administered herpes simplex virus 1 (HSV-1) that expresses human cytokine granulocyte-macrophage colony stimulating factor (GM-CSF) with antitumor and immune-stimulating activities.
Categories: DNA Viruses, Complex MixturesSodium acetate
go.drugbank.com/drugs/DB09395ApprovedInvestigationalSodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water.
Mixtures: Plasma-Lyte A, D-12043 Sol Conc Electrolyt Pour DialySynonyms: Acetato de sodioCelecoxib
go.drugbank.com/drugs/DB00482ApprovedInvestigationalCelecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other … [A181532] It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval in 1998.
Products: CELECOXIB 1A PHARMA 100MG, CELECOXIB 1A PHARMA 200MGLevoleucovorin
go.drugbank.com/drugs/DB11596ApprovedInvestigationalAs methotrexate functions as a DHFR inhibitor to prevent DNA synthesis in rapidly dividing cells, it also prevents the formation of DHF and THF. … This results in a deficiency of coenzymes and a resultant buildup of toxic substances that are responsible for numerous adverse side effects of methotrexate therapy.
Categories: Compounds used in a research, industrial, or household setting, Vitamin B ComplexDoxazosin
go.drugbank.com/drugs/DB00590ApprovedInvestigational[A180661] Because of its long-lasting effects, doxazosin can be administered once a day.[A180649] It is marketed by Pfizer and was initially approved by the FDA in 1990.[L7285]
Products: DOXAZOSIN 1 COR 1A PHARMA, DOXAZOSIN 2 COR 1A PHARMACandesartan cilexetil
go.drugbank.com/drugs/DB00796ApprovedInvestigationalUnlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough.
Mixtures: CANDESARTAN PL 1A 32/25, CANDESARTAN PL 1A 32/25Products: Candesartan A-med 8 mg Tabletten, Candesartan A-med 16 mg TablettenFencamfamin
go.drugbank.com/drugs/DB01463ApprovedIllicitWithdrawnFencamfamin (Glucoenergan, Reactivan) is a stimulant which was developed in the 1960s as an appetite suppressant. … Fencamfamin is used for treating depressive day-time fatigue, lack of concentration and lethargy. It is especially useful in patients with chronic conditions due to its favourable safety profile.