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Aducanumab
go.drugbank.com/drugs/DB12274ApprovedInvestigational[L34420] Biogen enrolled patients in phase 3 clinical trials in 2015 but increased the size of the trials from 1350 patients to 1650 patients to maintain statistical power in the face of a high standard … [A235720] Development of aducanumab was discontinued in March 2019 when two phase 3 clinical trials did not pass futility analysis; however, Biogen sought FDA approval in October 2019 after reanalyzing
Pantoprazole
go.drugbank.com/drugs/DB00213ApprovedInvestigationalat the secretory surface of gastric parietal cell. … It can also be found in quadruple regimens for the treatment of _H. pylori_ infections along with other antibiotics including [amoxicillin], [clarithromycin], and [metronidazole], for example.
Products: PANTOPRAZOLO EG, PANTO 40 MG IV ENJ. LIYOFILIZE TOZ ICEREN FLAKONDexpanthenol
go.drugbank.com/drugs/DB09357ApprovedInvestigationalFurthermore, it acts as a topical protectant, moisturizer, and has demonstrated anti-inflammatory properties [A32377]. … in the epithelium[A32373].
Synonyms: (2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamideMixtures: Multivit Et Fer Ampoules Et Comprimes, Dynam Ampoule Et TabletBeractant
go.drugbank.com/drugs/DB06761ApprovedThe final composition provides 25 mg/mL phospholipids (including 11.0-15.5 mg/mL disaturated phosphatidylcholine), 0.5-1.75 mg/mL triglycerides, 1.4-3.5 mg/mL free fatty acids, and less than 1.0 mg/mL … It is suspended in 0.9% sodium chloride solution, and heat-sterilized.
Products: Alveofact 45 mg/ml Pulver und Lösungsmittel zur Herstellung einer Suspension zur endotracheopulmonalen InstillationMepyramine
go.drugbank.com/drugs/DB06691ApprovedVet approvedIt has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered to be an unapproved prescription medication used for cough, cold, or allergic conditions. … It is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect.
Mixtures: PAMACET 500 MG/25 MG/15 MG FİLM KAPLI TABLET, 24 ADET, PAMACET 500 MG/25 MG/15 MG FİLM KAPLI TABLET, 40 ADETCategories: Antihistamines, Anesthetics, Etc.Serplulimab
go.drugbank.com/drugs/DB17451ApprovedInvestigationalMost recently, it was approved in the EU in February 2025 for the treatment of extensive-stage small cell lung cancer.[L52968,L52953] … It was first approved in China - where it is indicated for a number of different cancers[L52963] - and has since been approved in several southeast Asian countries.
Meropenem
go.drugbank.com/drugs/DB00760ApprovedInvestigationalIt is active against Gram-positive and Gram-negative bacteria. … In August 2017, a combination antibacterial therapy under the market name vabomere was approved for treatment of adult patients with complicated urinary tract infections (cUTI).
Synonyms: (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acidProducts: MERONEM 500 MG IV ENJ. ICIN TOZ ICEREN FLAKON, 1 ADET, MERONEM 1 GR IV ENJ. ICIN TOZ ICEREN FLAKON, 1 ADETBenzethonium
go.drugbank.com/drugs/DB11125ApprovedIt is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments. … It is shown to be effective in mediating its antimicrobial action against bacteria, fungi, mold and viruses.
Mixtures: Sanitary Wet Wipes, Disinfectant Wet WipesProducts: Antiseptic Skin Cream - 1mg/g, Ben E. Keith Foam SanitizerGabapentin
go.drugbank.com/drugs/DB00996ApprovedInvestigationalGabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid ([GABA]) that was first approved for use in the United States in 1993. … unlikely to participate in pharmacokinetic drug interactions.
Mixtures: GAVINDO NProducts: GABAPENTIN EG, GABAPENTIN - CT 100MG HARTSodium fluoride
go.drugbank.com/drugs/DB09325ApprovedInvestigationalSodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as [Fluoride ion F-18]. … The use of fluoride in dental practice began in the 1940s.
Mixtures: PREVENT 2 EN 1, E-Z CupsCategories: Compounds used in a research, industrial, or household setting