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Displaying results 1051 - 1060 of 10000 in total
  1. Drug

    Nelarabine

    go.drugbank.com/drugs/DB01280
    ApprovedInvestigational

    [L40878] T-cell acute lymphoblastic leukemia and lymphoma are relatively rare T-cells malignancy, with only 20 to 25% of patients diagnosed with acute lymphoblastic leukemia and 1.7% of patients diagnosed … [A2331,AA2334,A2335] Results from 2 phase 2 studies on adult and pediatric T-ALL/T-LBL indicated that nelarabine can yield a 13% complete response (CR) rate in pediatric patients and 18% in adult patients

    Synonyms: 2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purineProducts: NELARAMAX 250 MG/50 ML IV İNFÜZYONLUK ÇÖZELTİ , 6 ADET, NELARAMAX 250 MG/50 ML IV İNFÜZYONLUK ÇÖZELTİ , 1 ADET
  2. Drug

    Perazine

    go.drugbank.com/drugs/DB12710
    ApprovedWithdrawn

    Perazine has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.

    Products: PERAZIN-NEURAX 100 MG, PERAZIN-NEURAX 25 MG
  3. Drug

    Exemestane

    go.drugbank.com/drugs/DB00990
    ApprovedInvestigational

    It irreversibly binds to the active site of the enzyme resulting in permanent inhibition. … Exemestane is an oral steroidal aromatase inhibitor used in the adjuvant treatment of hormonally-responsive (also called hormone-receptor-positive, estrogen-responsive) breast cancer in postmenopausal

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: EXEMESTANE EG, AROMASIN 25 MG DRAJE, 30 ADET
  4. Drug

    Lanthanum carbonate

    go.drugbank.com/drugs/DB06792
    Approved

    It is used to treat elevated phosphate levels, primarily in patients with chronic kidney disease, by binding to dietary phosphate and preventing its absorption in the intestine.[L50733] … It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse effects.

    Products: ANTAX 1000 MG ORAL TOZ IÇEREN SAŞE ,30 SAŞE, ANTAX 1000 MG ORAL TOZ IÇEREN SAŞE ,90 SAŞE
  5. Drug

    Methocarbamol

    go.drugbank.com/drugs/DB00423
    ApprovedInvestigationalVet approved

    [Label,L6268] In Canada, methocarbamol can be sold as an over the counter oral medicine at a lower dose that may be combined with [acetaminophen] or [ibuprofen]. … Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether.

    Mixtures: MIYOREL 375 MG/300 MG TABLET, 20 ADET, Douleurs Musculaires Et Les Courbatures Extra Fort/muscle and Back Pain Relief Extra StrengthSynonyms: (RS)-2-hydroxy-3-(2-methoxyphenoxy)propyl carbamate
  6. Drug

    Protamine

    go.drugbank.com/drugs/DB13700
    ApprovedInvestigationalWithdrawn

    Products: PROTAMYN 1000® UI/ML AMPOLLA, Protamin Meda 1000 I.E./ml - Injektionslösung
  7. Drug

    Coagulation factor VIIa Recombinant Human

    go.drugbank.com/drugs/DB00036
    ApprovedInvestigational

    Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.

    Products: NOVOSEVEN RT 2 MG (100 KIU) ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ, NOVOSEVEN® RT 2 MG
  8. Drug

    Ivabradine

    go.drugbank.com/drugs/DB09083
    ApprovedInvestigational

    ≥70 beats per minute, who are not on beta-blockers due to contraindications or already receiving maximum beta-blocker dose. … Therefore, as ivabradine is designed as a "pure" heart rate-lowering drug by selectively acting on the If channels, it may offer a more favorable side effect profile due to its lower likelihood of causing

    Mixtures: IMPLICOR FILM-COATED TABLET 25 mg/5 mg, Implicor 50 mg/5 mg FilmtablettenCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 Substrates
  9. Drug

    Trastuzumab emtansine

    go.drugbank.com/drugs/DB05773
    ApprovedInvestigational

    Trastuzumab emtansine, formerly called Trastuzumab-DM1 (T-DM1) is a first-in-class HER2 antibody drug conjugate (ADC) comprised of Genentech's trastuzumab antibody linked to ImmunoGen's cell-killing agent … T-DM1 combines two strategies-- anti-HER2 activity and targeted intracellular delivery of the potent anti-microtubule agent, DM1 (a maytansine derivative)--to produce cell cycle arrest and apoptosis.

    Categories: HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors, Cytochrome P-450 SubstratesSynonyms: T-DM1
  10. Drug

    Fluticasone furoate

    go.drugbank.com/drugs/DB08906
    ApprovedInvestigational

    Fluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications[FDA Label][F4364]. Fluticasone furoate was first approved in 2007[L5965].

    Mixtures: RELVAR ELLIPTA 100/25 MCG KULLANIMA HAZIR INHALASYON TOZU ,3 X 30, REVINTY ELLIPTA 100/25 MCG KULLANIMA HAZIR INHALASYON TOZU, 30 D0ZCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers