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Displaying results 1061 - 1070 of 10000 in total
  1. Target

    Pepsin A-3

    go.drugbank.com/bio_entities/BE0012527
    TargetHumans

    Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent

    Polypeptides: Pepsin A-3
  2. Drug

    Tioconazole

    go.drugbank.com/drugs/DB01007
    Approved

    Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. … Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus".

    Mixtures: GYNOMAX L VAJINAL OVUL, 7 ADET, Gynecure Com.pk.vag Ont6.5%vulvar Crm1% W/wCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP3A Inhibitors
  3. Drug

    Voriconazole

    go.drugbank.com/drugs/DB00582
    ApprovedInvestigational

    Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. … [L15571] It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InhibitorsSynonyms: (R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol, (αR,βS)-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
  4. Target

    Streptogramin A acetyltransferase

    go.drugbank.com/bio_entities/BE0001238
    TargetEnterococcus faecium

    Inactivates the A compounds of streptogramin antibiotics by acetylation, thus providing resistance to these antibiotics.

    Polypeptides: Streptogramin A acetyltransferase
  5. Target

    Bacteriochlorophyll a protein

    go.drugbank.com/bio_entities/BE0001365
    TargetProsthecochloris aestuarii

    Intermediary in the transfer of excitation energy from the chlorophyll to the reaction centers.

    Polypeptides: Bacteriochlorophyll a protein
  6. Target

    Beta-glucosidase A

    go.drugbank.com/bio_entities/BE0001804
    TargetPaenibacillus polymyxa

    BglA is intracellular and cleaves cellobiose probably through inorganic phosphate mediated hydrolysis.

    Polypeptides: Beta-glucosidase A
  7. Target

    GABA(A) Receptor

    go.drugbank.com/bio_entities/BE0004797
    TargetHumans

    Extrasynaptic alpha-5-containing GABAARs in CA1 pyramidal neurons play a role in learning and memory processes (By similarity) … Plays an important role in somatosensation and in the production of antinociception (By similarity)

    Synonyms: GABA(A) receptor subunit alpha-1, GABA(A) receptor subunit alpha-2Function: GABA-A receptor activity, GABA-A receptor activity
  8. Target

    Apolipoprotein A-IV

    go.drugbank.com/bio_entities/BE0009049
    TargetHumans

    May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. … Apoa-IV is a major component of HDL and chylomicrons

    Polypeptides: Apolipoprotein A-IV
  9. Target

    HSP40, subfamily A

    go.drugbank.com/bio_entities/BE0009270
    TargetPlasmodium falciparum (isolate 3D7)

    Polypeptides: HSP40, subfamily ASynonyms: HSP40, subfamily A, putative
  10. Drug

    Potassium chloride

    go.drugbank.com/drugs/DB00761
    ApprovedInvestigationalWithdrawn

    A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.

    Mixtures: Plasma-Lyte A, Plasma-Lyte AInternational brands: Slow-K, Micro-K