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Displaying results 1061 - 1070 of 10000 in total
  1. Drug

    Efmarodocokin alfa

    go.drugbank.com/drugs/DB16398
    Investigational

    Efmarodocokin alfa is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).

    Synonyms: HUMAN INTERLEUKIN 22 (1-146), FUSED TO HUMAN IMMUNOGLOBULIN HEAVY CONSTANT GAMMA 4 (CH1(97-98), H(S10>P(158)), CH2(N67>G(227)))-(147-377), DIMER (156-156':159-159')-BISDISULFIDE, PRODUCED IN CHO CELLS,
  2. Drug

    Letermovir

    go.drugbank.com/drugs/DB12070
    ApprovedInvestigational

    [L1021] It is the first of a new class of CMV anti-infectives called DNA terminase complex inhibitors.[A31290] Letermovir has recieved both priority and orphan drug status from the FDA.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: PREVYMIS 240 MG SOLUCIÓN INYECTABLE, PREVYMİS 240 MG FİLM KAPLI TABLET, 28 ADET
  3. Drug

    Ganirelix

    go.drugbank.com/drugs/DB06785
    ApprovedInvestigational

    Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions.

    Products: ORGALUTRAN SOLUTION FOR INJECTION 0.25 mg/0.5 ml, ORGALUTRAN® 0.25 MG / 0.5 ML SOLUCION INYECTABLE
  4. Drug

    Telmisartan

    go.drugbank.com/drugs/DB00966
    ApprovedInvestigational

    blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a

    Mixtures: XIFEN A®80 /10 MG, TEMRED-A® TABLETAS 80 MG + 10 MG .Categories: Cytochrome P-450 Enzyme Inhibitors, Cytochrome P-450 CYP2C19 Inhibitors
  5. Drug

    Lactose

    go.drugbank.com/drugs/DB04465
    ApprovedInvestigationalWithdrawn

    A disaccharide of glucose and galactose in human and cow milk. It is used in pharmacy for tablets, in medicine as a nutrient, and in industry.

    Mixtures: SERECOR® FORTE DPI 100, SYNTHROID® 112 MCG TABLETASCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Deflazacort

    go.drugbank.com/drugs/DB11921
    Approved

    Deflazacort, also known as Emflaza, is a corticosteroid prodrug used as an agent to manage Duchenne Muscular Dystrophy (DMD).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: FLANTADIN 30 MG TABLET, 10 ADET, CLOBAK 6 MG
  7. Drug

    Levomenthol

    go.drugbank.com/drugs/DB00825
    ApprovedInvestigational

    Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils.

    Mixtures: KAMFOLIN 150 MG/G+100 MG/G MERHEM, 50 G, FENIDIN EKSPEKTORAN SURUP, 150 MLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  8. Drug

    Liothyronine

    go.drugbank.com/drugs/DB00279
    ApprovedInvestigationalVet approved

    Liothyronine is a thyroidal hormone T3 which is normally produced by the thyroid gland in a ratio 4:1 when compared with T4: T3. … Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine with bound iodine.

    Mixtures: BITIRON 50 MCG/12.5 MCG TABLET, 100 ADET, NP Thyroid 15Categories: l-Triiodothyronine
  9. Drug

    Duloxetine

    go.drugbank.com/drugs/DB00476
    ApprovedInvestigational

    Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. … [L6454] It has since received approval for a variety of indications including the treatment of neuropathic pain, Generalized Anxiety disorder, osteoarthritis, and stress incontinence.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: Duloxetin neuraxpharm 120 mg magensaftresistente Hartkapseln, DULOXETIN 1A PHARMA 20 MG
  10. Drug

    Glimepiride

    go.drugbank.com/drugs/DB00222
    ApprovedInvestigational

    Compared to [glipizide], another second SU drug, glimepiride has a longer duration of action. … It is sometimes classified as a third-generation SU because it has larger substitutions than other second-generation SUs.

    Mixtures: METGLITAL LEX 850 MG / 2 MG TABLETAS DE LIBERACION PROLONGADA, METGLITAL LEX 850 MG / 2 MG TABLETAS DE LIBERACION PROLONGADACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates