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Hydrocortisone
go.drugbank.com/drugs/DB00741ApprovedInvestigationalVet approved[A188420] Hydrocortisone was granted FDA approval on 5 August 1952.[L10574] … [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone.
Mixtures: Activir Duo 50 mg/g + 10 mg/g Creme, Oto End 10Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InducersRifabutin
go.drugbank.com/drugs/DB00615ApprovedInvestigationalA broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersSynonyms: 1,4-Dihydro-1-deoxy-1',4-didehydro-5'-(2-methylpropyl)-1-oxorifamycin XIVTeniposide
go.drugbank.com/drugs/DB00444ApprovedInvestigationalTeniposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and pr...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesProducts: VUMON VM 26 INYECTABLE X 50 MG / 5MLBenfotiamine
go.drugbank.com/drugs/DB11748ApprovedInvestigationalWithdrawnBenfotiamine has been investigated for the treatment and prevention of Diabetic Nephropathy and Diabetes Mellitus, Type 2.
Products: B-Gamma 150 mg Film Kaplı Tablet (30 adet), Benfodian 150 mg Film Kaplı Tablet (30 adet)Interferon beta-1b
go.drugbank.com/drugs/DB00068ApprovedInvestigationalProduced in E. coli, no carbohydrates, MW=18.5kD
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: BETAFERON FOR INJECTION 0.25 mg/mlBisacodyl
go.drugbank.com/drugs/DB09020ApprovedInvestigational[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a laxative since 1952.[A233300] … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).
Mixtures: BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADET, PCP 100 KitSynonyms: Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester)Entecavir
go.drugbank.com/drugs/DB00442ApprovedInvestigationalIt is marketed under the trade name Baraclude (BMS). … It was approved by the U.S. Food and Drug Administration (FDA) in March 2005.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: VORIX® 1.0 MG, OVAMET 1 MG FILM KAPLI TABLET,30 ADETCeritinib
go.drugbank.com/drugs/DB09063ApprovedInvestigationalThe FDA approved ceritinib in April 2014 due to a surprisingly high response rate (56%) towards crizotinib-resistant tumours and has designated it with orphan drug status. … This occurrence led to development of novel second-generation ALK inhibitors such as ceritinib to overcome crizotinib resistance.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InhibitorsSynonyms: N-{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propane-2-sulfonamidePentazocine
go.drugbank.com/drugs/DB00652ApprovedVet approvedIt is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Products: Pentazocine-Fresenius 30 mg/ml injection, Talwin - Liq 30mg/mlMagnesium chloride
go.drugbank.com/drugs/DB09407ApprovedInvestigationalMagnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.
Mixtures: DESOLITE BFS IV INFÜZYON IÇIN ÇÖZELTI,500 ML SETLI, DESOLITE BFS IV INFÜZYON IÇIN ÇÖZELTI,500 ML SETSIZProducts: Slow-mag, Slow-mag-tab