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Displaying results 1071 - 1080 of 10000 in total
  1. Pathway

    Metabolism and Physiological Effects of N-alpha-Acetyl-L-arginine

    smpdb.ca/view/SMP0125530
    Metabolic

    N-Acetylarginine can also be classified as an alpha amino acid or a derivatized alpha amino acid. … Uremic toxins are a diverse group of endogenously produced molecules that, if not properly cleared or eliminated by the kidneys, can cause kidney damage, cardiovascular disease and neurological deficits

    Drugs: Pyridoxal phosphate · Arginine · Aspartic acid · Ornithine · L-Glutamine · Adenosine phosphate +10 more
  2. Pathway

    Ziconotide NMDA and Substance P Receptor Pain Inhibition Action Pathway

    smpdb.ca/view/SMP0126347
    Drug action

    Nociceptive pain signalling is a complex processing pathway involving peripheral nociceptors, primary afferent nerve fibres, and downstream CNS neurons located in the spinal cord such as the dorsal root … Ziconotide inhibits Voltage-dependent N-type calcium channels in presynaptic neurons.

    Drugs: Glutamic acid · Calcium · Sar9, Met (O2)11-Substance P · Ziconotide
  3. Drug

    Lanthanum carbonate

    go.drugbank.com/drugs/DB06792
    Approved

    It is used to treat elevated phosphate levels, primarily in patients with chronic kidney disease, by binding to dietary phosphate and preventing its absorption in the intestine.[L50733] … It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse effects.

    Categories: Drugs for Treatment of Hyperkalemia and HyperphosphatemiaProducts: FOSRENOL CHEWABLE TABLETS 500MG, Fosrenol Chewable Tablets 500mg
  4. Drug

    Gadoteric acid

    go.drugbank.com/drugs/DB09132
    ApprovedInvestigational

    [A263141,A263106] Gadoterate is approved by the FDA under the brand name DOTAREM on 20th March 2013 for intravenous uses with magnetic resonance imaging (MRI) in the brain (intracranial), spine, and … associated tissues in adult and pediatric patients (2 years of age and older) to detect and visualize areas with disruption of the blood-brain barrier (BBB) and/or abnormal vascularity.

    Categories: Compounds used in a research, industrial, or household settingProducts: CLARISCAN SOLUTION FOR INJECTION IN VIAL 0.5 MMOL/ML, Clariscan 0,5 mmol/ml Injektionslösung in einer Fertigspritze
  5. Drug

    Tenofovir disoproxil

    go.drugbank.com/drugs/DB00300
    ApprovedInvestigational

    This drug is prescribed in combination with other drugs for the management of HIV infection as well as for Hepatitis B therapy. Tenofovir disoproxil was initially approved in 2001 [FDA label]. … Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name _Viread_, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase

    Mixtures: STRIBILD 150MG/150MG/200MG/245MG FILM KAPLI TABLET, 90 ADET, STRIBILD 150MG/150MG/200MG/245MG FILM KAPLI TABLET, 30 ADETCategories: Antivirals used in combination for the treatment of HIV infections, Tenofovir and prodrugs
  6. Drug

    Disulfiram

    go.drugbank.com/drugs/DB00822
    ApprovedInvestigational

    A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. … and other symptoms (acetaldehyde syndrome).

    Synonyms: N,N,N',N'-tetraethylthiuram disulfide, 1,1'-dithiobis(N,N-diethylthioformamide)Categories: Drugs Used in Alcohol Dependence, Drugs Used in Addictive Disorders
  7. Drug

    Zotepine

    go.drugbank.com/drugs/DB09225
    ApprovedWithdrawn

    [A31855] It has been used as an antipsychotic in Japan, India and some places in Europe like UK and Germany since 1980's.[A31857] Zotepine was never approved by the FDA. … In 1993, it was classified as inactive drug substance (Status I, Type II) and in 1995 the FDA studied the manufacturing procedures of Zotepine tablets in Germany, but the status remained inactive.

    Products: ZOLEPTILO 25MG TABLETAS RECUBIERTAS
  8. Drug

    Cysteine

    go.drugbank.com/drugs/DB00151
    ApprovedInvestigationalNutraceutical

    A thiol-containing non-essential amino acid that is oxidized to form cystine.

    Mixtures: PF K-CAMINE %8 AMINO ASIT IV INFUZYON ICIN COZELTI, 1000 ML (SETLI), PF K-CAMINE %8 AMINO ASIT IV INFUZYON ICIN COZELTI, 1000 ML (SETSIZ)Categories: Amino Acids, Peptides, and Proteins
  9. Drug

    Solenopsis richteri

    go.drugbank.com/drugs/DB11026
    Approved

    Solenopsis richteri allergenic extract is used in allergenic testing. It is extracted from the black imported fire ant which is native to South Amercia. … The species has also been introduced in North Amercia. When stung, the bites are characterized by sterile pustules that are surrounded by reddened swelling along with redness extending beyond.

    Synonyms: black imported fire ant allergenic extractMixtures: Insects whole body, Fire Ant Mix, Insects whole body, Fire Ant Mix
  10. Drug

    Desmopressin

    go.drugbank.com/drugs/DB00035
    ApprovedInvestigational

    Despite its versatility, desmopressin carries a Boxed Warning regarding the risk of hyponatremia (critically low blood sodium levels), which can lead to seizures and death if fluid intake is not properly … It is considered a first-line therapy for central diabetes insipidus but is ineffective in patients with nephrogenic diabetes insipidus, where the kidneys are non-responsive to the hormone [A275458, L56105

    Categories: Pituitary and Hypothalamic Hormones and Analogues, Sex Hormones and InsulinsProducts: NOCDURNA ORAL LYOPHILISATE 25MCG, NOCDURNA ORAL LYOPHILISATE 50MCG