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Calcium
go.drugbank.com/drugs/DB01373ApprovedInvestigationalNutraceuticalCalcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. … Circulating calcium is either in the free, ionized form or bound to blood proteins such as serum albumin. Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day.
Mixtures: Multi II IV Vi Tab, Vc IIProducts: AAR OS NGlutamic acid
go.drugbank.com/drugs/DB00142ApprovedInvestigationalNutraceuticalA peptide that is a homopolymer of glutamic acid.
Mixtures: Aminosyn II in Dextrose, Aminosyn II in DextroseNuclear receptor subfamily 4 group A member 3
go.drugbank.com/bio_entities/BE0008998TargetHumansTranscriptional activator that binds to regulatory elements in promoter regions in a cell- and response element (target)-specific manner. … Binds to NBRE motif in CCND1 promoter, resulting in the activation of the promoter and CCND1 transcription (By similarity).
Synonyms: Translocated in extraskeletal chondrosarcomaSerine/threonine-protein kinase Nek4
go.drugbank.com/bio_entities/BE0009498TargetHumansRequired for normal cell cycle arrest in response to double-stranded DNA damage
Synonyms: Never in mitosis A-related kinase 4Avobenzone
go.drugbank.com/drugs/DB09495ApprovedInvestigationalIt is included in many commercially available sunscreens which are used as wide spectrum sunscreens. … Avobenzone is very sensitive to light, to increase its stability and duration of action, photostablizers are added in the sunscreen product. Avobenzone has an absorption maximum of 357 nm.
Mixtures: Bullet Line, Bullet LineCategories: Compounds used in a research, industrial, or household settingCamizestrant
go.drugbank.com/drugs/DB19218ApprovedInvestigational[L64117,L64107,L64116] It is the first next-generation oral SERD and complete ER antagonist approved in the first-line setting, and the only one approved for use with all three widely approved CDK4/6 inhibitors … [L64094,L64107] Patients are selected for treatment on the basis of an *ESR1* mutation detected by circulating tumor DNA testing during first-line endocrine therapy, before radiographic disease progression
Synonyms: 3-pyridinamine, n-(1-(3-fluoropropyl)-3-azetidinyl)-6-((6s,8r)-6,7,8,9-tetrahydro-8-methyl-7-(2,2,2-trifluoroethyl)-3h-pyrazolo(4,3-f)isoquinolin-6-yl)-, N-(1-(3-fluoropropyl)-3-azetidinyl)-6-((6s,8r)-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydro-3h-pyrazolo(4,3-f)isoquinolin-6-yl)-3-pyridinamineOstrea edulis shell
go.drugbank.com/drugs/DB14251InvestigationalOstrea edulis shell is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: European Flat Oyster ShellGriseofulvin
go.drugbank.com/drugs/DB00400ApprovedVet approvedAn antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.
Stromal cell-derived factor 1
go.drugbank.com/bio_entities/BE0001150TargetHumansInduces down-regulation and internalization of ACKR3 expressed in various cells. … Binds to the allosteric site (site 2) of integrins and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 in a CXCR4-independent manner (PubMed:29301984).
Synonyms: Intercrine reduced in hepatomasNuclear factor NF-kappa-B p100 subunit
go.drugbank.com/bio_entities/BE0002387TargetHumansNF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. … In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which
Synonyms: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2