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Hypoxia-inducible factor 1
go.drugbank.com/bio_entities/BE0010297TargetHumansForms heterodimers with the aryl hydrocarbon receptor (AHR) to mediate the transcriptional response to xenobiotics by binding xenobiotic response elements (XREs) or dioxin response elements (DREs) in target
Polypeptides: Aryl hydrocarbon receptor nuclear translocatorSynonyms: Dioxin receptor, nuclear translocatorTranslocator protein
go.drugbank.com/bio_entities/BE0000736TargetHumansWas initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:1847678)
Synonyms: Mitochondrial benzodiazepine receptor, Peripheral-type benzodiazepine receptorP2Y purinoceptor 14
go.drugbank.com/bio_entities/BE0009825TargetHumansReceptor for UDP-glucose and other UDP-sugar coupled to G-proteins. Not activated by ATP, ADP, UTP or ATP
Synonyms: UDP-glucose receptor, G protein-coupled receptor 105Function: G protein-coupled purinergic nucleotide receptor activityATP-binding cassette sub-family C member 9
go.drugbank.com/bio_entities/BE0000469TargetHumansSubunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation (PubMed:9831708). Can form a sulfo...
Synonyms: Sulfonylurea receptor 2NKG2-D type II integral membrane protein
go.drugbank.com/bio_entities/BE0010415TargetHumansActs as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. … Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected
Synonyms: NK cell receptor D, NKG2-D-activating NK receptorTransmembrane anterior posterior transformation protein 1 homolog
go.drugbank.com/bio_entities/BE0003506TargetHumansPlays a role in primary cilia formation (PubMed:26365339). May act as a downstream effector of HOXC8 possibly by transducing or transmitting extracellular information required for axial skeletal patterning during development (By similari...
Synonyms: Cytomegalovirus partial fusion receptorFunction: growth hormone-releasing hormone receptor activityRibosome-binding protein 1
go.drugbank.com/bio_entities/BE0003466TargetHumansActs as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane
Synonyms: Ribosome receptor protein, 180 kDa ribosome receptor homologNatural killer cells antigen CD94
go.drugbank.com/bio_entities/BE0010559TargetHumansImmune receptor involved in self-nonself discrimination.
Synonyms: NK cell receptor, Killer cell lectin-like receptor subfamily D member 1Function: HLA-A specific activating MHC class I receptor activityV-type immunoglobulin domain-containing suppressor of T-cell activation
go.drugbank.com/bio_entities/BE0010797TargetHumansImmunoregulatory receptor which inhibits the T-cell response (PubMed:24691993). May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity).
Synonyms: Platelet receptor Gi24, V-set immunoregulatory receptorIntegrin beta-7
go.drugbank.com/bio_entities/BE0003414TargetHumansIntegrin ITGAE/ITGB7 (alpha-E/beta-7, HML-1) is a receptor for E-cadherin (PubMed:10837471) … Integrin ITGA4/ITGB7 (alpha-4/beta-7) (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT) (Probable
Synonyms: Gut homing receptor beta subunit