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Displaying results 1081 - 1090 of 6198 in total
  1. Drug

    Brincidofovir

    go.drugbank.com/drugs/DB12151
    ApprovedInvestigational

    Brincidofovir, developed by Chimerix under the brand name Tembexa, was approved by the FDA for the treatment of smallpox infection in June 2021. … Brincidofovir is an oral antiviral drug used in the treatment of human smallpox infections.

  2. Drug

    Streptomycin

    go.drugbank.com/drugs/DB01082
    ApprovedInvestigationalVet approved

    Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and used in practice in the 1940s.

  3. Drug

    Sonidegib

    go.drugbank.com/drugs/DB09143
    ApprovedInvestigational

    Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) developed as an anticancer agent by Novartis. It was FDA approved in 2015 for the treatment of basal cell carcinoma.

  4. Drug

    Elivaldogene autotemcel

    go.drugbank.com/drugs/DB16746
    Approved

    It is used to provide functional copies of human adrenoleukodystrophy protein (ALDP) in patients with adrenoleukodystrophy,[L39491] an X-linked genetic disorder characterized by missing or non-functional … [L40298] In September 2022, Skysona was approved by the FDA.[L43247]

  5. Drug

    Autologous cultured chondrocytes

    go.drugbank.com/drugs/DB10997
    ApprovedInvestigational

    The surgical implantation shows a tolerable safety profile and efficacy up to 4 years, but it is not indicated for patients with osteoarthritis. … It serves as an alternative repair treatment for patients with inadequate response to pre-existing surgical methods.

  6. Drug

    Levocabastine

    go.drugbank.com/drugs/DB01106
    Approved

    Levocabastine is a selective second-generation H1-receptor antagonist used for allergic conjunctivitis. Levocabastine was discovered at Janssen Pharmaceutica in 1979.

  7. Drug

    Paliperidone

    go.drugbank.com/drugs/DB01267
    ApprovedInvestigational

    The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. … Paliperidone was approved by the FDA for treatment of schizophrenia on December 20, 2006.

  8. Target

    Carbonic anhydrase 1

    go.drugbank.com/bio_entities/BE0000267
    TargetEnzymeCarrierHumans

    Can hydrate cyanamide to urea (PubMed:10550681)

    Synonyms: CAB, CA-I
  9. Target

    Carbonic anhydrase 2

    go.drugbank.com/bio_entities/BE0000322
    TargetEnzymeCarrierHumans

    Can also hydrate cyanamide to urea (PubMed:10550681, PubMed:11015219). Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (PubMed:15990874).

    Synonyms: CAC, CA-II
  10. Drug

    Selenious acid

    go.drugbank.com/drugs/DB11127
    Approved

    Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. … It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties.