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Displaying results 1081 - 1090 of 10000 in total
  1. Drug

    Phenoxyethanol

    go.drugbank.com/drugs/DB11304
    ApprovedInvestigational

    It is produced by reacting phenol (EU) and ethylene oxide (EU) at a high temperature and pressure. This substance occurs naturally in green tea (EU) [L2621]. … Phenoxyethanol has been classified as an antimicrobial and preservative by Health Canada [L2623].

    Mixtures: Linola sept 1 mg/g + 10 mg/g Wund-Gel, HydroGold 9Synonyms: 1-Hydroxy-2-phenoxyethane, 2-phenoxyethanol
  2. Drug

    Beclamide

    go.drugbank.com/drugs/DB09011
    Experimental

    Beclamide (N-benzyl-B-chloropropionamide) is a no longer used drug that possesses anticonvulsant and sedative activity.

  3. Drug

    Tetradecyl hydrogen sulfate (ester)

    go.drugbank.com/drugs/DB11328
    Approved

    Sodium tetradecyl sulfate has been widely used since the 1950s, and in 1978 the first successful report of injecting a 1% solution into spider angiomas in 144 patients was made. … Also noted was an unspecified number of episodes of epidermal necrosis without significant long-term effects and a 30% incidence of post-sclerosis pigmentation that resolved within a few months [L2035]

    Synonyms: 7-Ethyl-2-methyl-4-undecanol sulfateInternational brands: Fibro-Vein 3%
  4. Drug

    Nonivamide

    go.drugbank.com/drugs/DB11324
    Approved

    This drug has been studied in combination with Nicarboxil in the treatment of lower back pain [L2642]. … Nonivamide is a flavoring ingredient. Nonivamide is an organic compound and a capsaicinoid. It is an amide of pelargonic acid and _vanillylamine_.

    Mixtures: Nonivamid + Nicoboxil Zentiva 4 mg/g + 25 mg/g SalbeSynonyms: N-Vanillylnonamide, N-Nonanoyl vanillylamide
  5. Drug

    Chromium

    go.drugbank.com/drugs/DB11136
    ApprovedInvestigational

    Chromium deficiency has been associated with a diabetic-like state, impaired growth, decreased fertility and increased risk of cardiovascular diseases [A32343, A32351, L1982]. … Chromium is a transition element with the chemical symbol Cr and atomic number 24 that belongs to Group 6 of the periodic table.

    Mixtures: GNC Mega Teen, BLACKMORES teen multi for GIRLS capsuleProducts: .-1, Wms 1
  6. Drug

    Ataluren

    go.drugbank.com/drugs/DB05016
    ApprovedWithdrawn

    More specifically, ataluren is used in the small group of patients whose disease is caused by a specific genetic defect (called a ‘nonsense mutation’) in the dystrophin gene. … Ataluren is a novel, orally administered drug that targets nonsense mutations.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid
  7. Target

    High affinity immunoglobulin epsilon receptor subunit gamma

    go.drugbank.com/bio_entities/BE0000049
    TargetHumans

    As a component of the high-affinity immunoglobulin E (IgE) receptor, mediates allergic inflammatory signaling in mast cells. … As a constitutive component of interleukin-3 receptor complex, selectively mediates interleukin 4/IL4 production by basophils, priming T-cells toward effector T-helper 2 subset.

    Polypeptides: High affinity immunoglobulin epsilon receptor subunit gammaSynonyms: Fc receptor gamma-chain, IgE Fc receptor subunit gamma
  8. Target

    Gamma-aminobutyric acid receptor subunit rho-1

    go.drugbank.com/bio_entities/BE0000129
    TargetHumans

    Rho subunit of the pentameric ligand-gated chloride channels responsible for mediating the effects of gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain (PubMed:37659407). Rho-containing GABA-gated chlorid...

    Polypeptides: Gamma-aminobutyric acid receptor subunit rho-1Synonyms: GABA(C) receptor, GABA(A) receptor subunit rho-1
  9. Target

    Mast/stem cell growth factor receptor Kit

    go.drugbank.com/bio_entities/BE0000453
    TargetHumans

    KIT signaling is modulated by protein phosphatases, and by rapid internalization and degradation of the receptor. … Tyrosine-protein kinase that acts as a cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance

    Polypeptides: Mast/stem cell growth factor receptor Kit
  10. Target

    Gamma-aminobutyric acid receptor subunit alpha-4

    go.drugbank.com/bio_entities/BE0000478
    TargetHumans

    Alpha subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:35355020). GABA-gated chloride channels, also named GABA(A) receptors (...

    Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-4Synonyms: GABA(A) receptor subunit alpha-4