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Displaying results 101 - 110 of 453 in total
  1. Target

    Retinoic acid-induced protein 3

    go.drugbank.com/bio_entities/BE0000697
    TargetHumans

    This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G protein signaling pathways. Functions as a negative modulator of EGFR signaling (By similarity). … Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells.

    Polypeptides: Retinoic acid-induced protein 3Synonyms: Retinoic acid-induced gene 1 protein
  2. Target

    Excitatory amino acid transporter 3

    go.drugbank.com/bio_entities/BE0001054
    TargetTransporterHumans

    Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:26690923, PubMed:8857541). … Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:21123949, PubMed:26690923, PubMed:33658209, PubMed:7521911, PubMed

    Polypeptides: Excitatory amino acid transporter 3Synonyms: Neuronal and epithelial glutamate transporter, Excitatory amino-acid carrier 1
  3. Target

    Uric acid degradation bifunctional protein

    go.drugbank.com/bio_entities/BE0001313
    TargetBacillus sp. (strain TB-90)

    Catalyzes two steps in the degradation of uric acid, i.e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline … (OHCU) to (S)-allantoin (By similarity).

    Polypeptides: Uric acid degradation bifunctional protein
  4. Target

    Fatty acid-binding protein, brain

    go.drugbank.com/bio_entities/BE0001821
    CarrierTargetHumans

    It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (By similarity)

    Polypeptides: Fatty acid-binding protein, brainSynonyms: Fatty acid-binding protein 7, Brain-type fatty acid-binding protein
  5. Target

    Fatty acid-binding protein 5

    go.drugbank.com/bio_entities/BE0001984
    CarrierTargetHumans

    Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; which promotes proliferation and survival. … Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind.

    Polypeptides: Fatty acid-binding protein 5Synonyms: Fatty acid-binding protein, epidermal, Epidermal-type fatty acid-binding protein
  6. Target

    Branched-chain-amino-acid aminotransferase

    go.drugbank.com/bio_entities/BE0002016
    TargetEscherichia coli (strain K12)

    Acts on leucine, isoleucine and valine.

    Polypeptides: Branched-chain-amino-acid aminotransferaseFunction: branched-chain-amino-acid transaminase activity
  7. Target

    Aromatic-L-amino-acid decarboxylase

    go.drugbank.com/bio_entities/BE0002151
    TargetEnzymeHumans

    Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine and L-5-hydroxytryptophan to serotonin

    Polypeptides: Aromatic-L-amino-acid decarboxylase
  8. Target

    Acidic amino acid decarboxylase GADL1

    go.drugbank.com/bio_entities/BE0002163
    TargetHumans

    May catalyze the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. … Does not exhibit any decarboxylation activity toward glutamate

    Polypeptides: Acidic amino acid decarboxylase GADL1Synonyms: Cysteine sulfinic acid decarboxylase
  9. Target

    Cyclopropane mycolic acid synthase 1

    go.drugbank.com/bio_entities/BE0003738
    TargetMycobacterium tuberculosis

    Catalyzes the conversion of a double bond to a cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine. … Cyclopropanated mycolic acids are key factors participating in cell envelope permeability, host immunomodulation and persistence.

    Polypeptides: Cyclopropane mycolic acid synthase 1Synonyms: Cyclopropane fatty acid synthase, Mycolic acid methyltransferase
  10. Target

    Fatty acid-binding protein, liver

    go.drugbank.com/bio_entities/BE0003998
    CarrierTargetHumans

    Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity)

    Polypeptides: Fatty acid-binding protein, liverSynonyms: Fatty acid-binding protein 1, Liver-type fatty acid-binding protein