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Alprenolol Action Pathway
smpdb.ca/view/SMP0000297Drug actionAlprenolol (also known as alfeprol, alpheprol or alprenololum) a beta blocker (non-selective) that block beta-1 adrenergic receptor in heart. Blocking beta-1 adrenergic receptor could prevent the binding of epinephrine and norepinephrine...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Betaxolol Action Pathway
smpdb.ca/view/SMP0000299Drug actionBetaxolol (also known as Betoptic or Lokren) is a selective beta blocker that can block beta1-adrenergic receptors and beta2-adrenergic receptors. Blocking of beta1-adrenergic receptors in heart and vascular smooth muscle can lead to red...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Esmolol Action Pathway
smpdb.ca/view/SMP0000301Drug actionEsmolol, sold as Brevibloc, is a cardioselective beta-1 receptor blocker drug. As a beta-blocker, esmolol blocks the agonistic effect of the sympathetic neurotransmitters by competing for receptor binding sites, and as it is cardioselect...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Nadolol Action Pathway
smpdb.ca/view/SMP0000303Drug actionNadolol (also known as Corgard or Solgol) is a beta blocker (non-selective) that are used for treat high blood pressure or chest pain. Nadolol bind to beta1-adrenergic receptors in heart and vascular smooth muscle to block the binding of...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Oxprenolol Action Pathway
smpdb.ca/view/SMP0000304Drug actionOxprenolol (also known as Trasacor or Trasicor) is a beta blocker (non-selective) that are used for treat high blood pressure or chest pain. Oxprenolol bind to beta1-adrenergic receptors in heart and vascular smooth muscle to block the b...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Propranolol Action Pathway
smpdb.ca/view/SMP0000307Drug actionPropranolol, a non-cardioselective beta blocker, inhibits sympathetic stimulation by competing with neurotransmitters like catecholamines to bind beta(1)-adrenergic receptors of the heart and vascular smooth muscle. Propranolol binding r...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Nebivolol Action Pathway
smpdb.ca/view/SMP0000366Drug actionNebivolol (also known as Bystolic or Nebivololum) is a β1-receptor blocker (selective β1-receptor antagonist) that can bind and inhibit Beta-1 adrenergic receptor in muscule and heart. Nebivolol competes with epinephrine or other beta-...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Nifedipine Action Pathway
smpdb.ca/view/SMP0000379Drug actionNifedipine (also known as Adalat or Procardia) is a dihydropyridine calcium channel blocker that may be used for treatment of hypertension and exertion-related angina in the absence of vasospasm. Nifedipine binds the major channel in mus...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Nimodipine Action Pathway
smpdb.ca/view/SMP0000380Drug actionNimodipine (also known as Nimotop or Periplum) is a dihydropyridine calcium channel blocker that may not be used for treatment of hypertension. Compared to other DHP CCBs, nimodipine is more active in the cerebral vasculature than in the...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Nisoldipine Action Pathway
smpdb.ca/view/SMP0000381Drug actionNisoldipine (also known as Sular or Nisocor) is a dihydropyridine calcium channel blocker that may be used for treatment of hypertension, chronic stable angina and Prinzmetal's variant angina. Nisoldipine binds the major channel in muscl...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4