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Chlorhexidine
go.drugbank.com/drugs/DB00878ApprovedInvestigationalVet approvedWithdrawn[L43942,L44027] Other formulations of chlorhexidine continue to be available. … [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two biguanide groups joined by a central hexamethylene chain.
Iopromide
go.drugbank.com/drugs/DB09156Approved[A260751] Approved by the FDA in 1995 and Health Canada in 1994 under the brand name ULTRAVIST, iopromide is used in radiological diagnosis, including, but not limited to, intra-arterial digital subtraction … It functions as a contrast agent by opacifying blood vessels in the flow path of the contrast agent, permitting radiographic visualization of the internal structures until significant hemodilution occurs
Eugenol
go.drugbank.com/drugs/DB09086ApprovedInvestigationalThere are a number of unapproved OTC products available containing eugenol that advertise its use for the treatment of toothache. … Eugenol is a naturally occurring phenolic molecule found in several plants such as cinnamon, clove, and bay leaves.
Cyclobenzaprine
go.drugbank.com/drugs/DB00924ApprovedInvestigationalCyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been available for human use since 1977. … [A184982] It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from [Amitriptyline] by only a single double bond.
Panic Disorder
go.drugbank.com/conditions/DBCOND0006063Imlifidase
go.drugbank.com/drugs/DB15258ApprovedInvestigational[A225916] Currently available treatments for end-stage renal disease are limited to dialysis and renal transplantation, with the former associated with significant costs and lower quality of life. … [A225836,A225921] Imlifidase is a cysteine protease and eliminates Fc-dependent effector functions such as CDC and ADCC by cleaving the heavy chains of human immunoglobulin G (IgG) antibodies.
Enlicitide
go.drugbank.com/drugs/DB22580ApprovedInvestigationalavailable to clear low-density lipoprotein cholesterol (LDL-C), thereby lowering circulating LDL-C levels. … (CORALreef Lipids), and by 59% in patients with HeFH (CORALreef HeFH), with comparable reductions in non-HDL-C and apolipoprotein B.
Fluticasone furoate
go.drugbank.com/drugs/DB08906ApprovedInvestigationalFluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications[FDA Label][F4364]. Fluticasone furoate was first approved in 2007[L5965].
Ibuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigationalIt was the first available over-the-counter NSAID.[A39076] On the available products, ibuprofen is administered as a racemic mixture. … Once administered, the R-enantiomer undergoes extensive interconversion to the S-enantiomer _in vivo_ by the activity of the alpha-methylacyl-CoA racemase.
Mixtures: Period Pills by BiikayProducts: Ibuprofen 24/7 Life by 7-Eleven, Ibuprofen, Solubilized 24/7 Life by 7-ElevenFactor IX Complex (Human)
go.drugbank.com/drugs/DB11330ApprovedInvestigationalMany commercially available products also contain low levels of other antithrombotic proteins. … As the product Kcentra, Factor IX Complex is also indicated for the urgent reversal of acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients