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Amsacrine
go.drugbank.com/drugs/DB00276ApprovedInvestigationalWithdrawnAminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in c...
Categories: P-glycoprotein inhibitorsInternational brands: AMSA P-DSulodexide
go.drugbank.com/drugs/DB06271ApprovedInvestigationalWithdrawnSulodexide is a mixture of glycosaminoglycans (GAGs) composed of dermatan sulfate (DS) and fast moving heparin (FMH).
Products: VESSEL DUE F, VESSEL DUE F 250 LSU CAPSULETacrolimus
go.drugbank.com/drugs/DB00864ApprovedInvestigationalTacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection.
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: Envarsus Pa, PROGRAF® XL CAPSULAS DE LIBERACIONPROLONGADA DE 1 MGDigoxin
go.drugbank.com/drugs/DB00390ApprovedInvestigational[L9143] This drug originates from the foxglove plant, also known as the _Digitalis_ plant[T610], studied by William Withering, an English physician and botanist in the 1780s.
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: LANOXIN PG 62.5MCG TABLETS, LANOXIN-PG PAEDIATRIC/GERIATRIC TABLET 0.0625 mgIron sucrose
go.drugbank.com/drugs/DB09146ApprovedInvestigationalDue to less side effects than iron dextran, iron sucrose is more preferred in chronic kidney disease patients. … saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do
Products: KON. COZ. ICEREN 5 AMPUL, FEX-VANPosaconazole
go.drugbank.com/drugs/DB01263ApprovedInvestigationalVet approvedPosaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: POSACONAZOLO DR. REDDY'S, NOXAFIL ® TABLETAS RECUBIERTAS DE LIBERACIÓN RETARDADAHydroxychloroquine
go.drugbank.com/drugs/DB01611ApprovedInvestigationalHydroxychloroquine is a racemic mixture consisting of an R and S enantiomer.[A183047] Hydroxychloroquine is an aminoquinoline like [chloroquine].
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: HYDROXYCHLOROQUIN DR EB200, PLAQUINOL® TABLETAS DE 400 MGTimolol
go.drugbank.com/drugs/DB00373ApprovedInvestigationalTimolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. … [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management of conditions such as open-angle glaucoma and hypertension.
Mixtures: Van-dorzolamide-timolol, COMBIGAN-DCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesLatanoprost
go.drugbank.com/drugs/DB00654ApprovedInvestigationalAnother benefit latanoprost is that it can be administered once a day.[A184490]
Mixtures: Tim-Lat -PF, Akistan Duo 50 Mikrogramm/ml + 5 mg/ml Augentropfen, LösungProducts: GAAP OFTENO LIBRE DE CONSERVADORES, Latanoprost PF