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Displaying results 101 - 110 of 4358 in total
  1. Drug

    Tacrolimus

    go.drugbank.com/drugs/DB00864
    ApprovedInvestigational

    Tacrolimus is chemically known as a macrolide. It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex.

    Products: Qvaya 1 mg/ml Emulsion zur Anwendung auf der Haut, TACROLIMUS MYLAN GENERICS
  2. Target

    Potassium voltage-gated channel subfamily A member 1

    go.drugbank.com/bio_entities/BE0000781
    TargetHumans

    The channel alternates between opened and closed conformations in response to the voltage difference across the membrane (PubMed:19912772). … Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the kidney (PubMed:19903818, PubMed

    Polypeptides: Potassium voltage-gated channel subfamily A member 1Synonyms: Voltage-gated K(+) channel HuKI, Voltage-gated potassium channel HBK1
  3. Target

    Potassium voltage-gated channel subfamily A member 7

    go.drugbank.com/bio_entities/BE0004719
    TargetHumans

    Mediates the voltage-dependent potassium ion permeability of excitable membranes. … Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with

    Polypeptides: Potassium voltage-gated channel subfamily A member 7Synonyms: Voltage-gated potassium channel subunit Kv1.7
  4. Target

    Potassium voltage-gated channel subfamily B member 1

    go.drugbank.com/bio_entities/BE0004721
    TargetHumans

    The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. … Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in the pancreas and cardiovascular system.

    Polypeptides: Potassium voltage-gated channel subfamily B member 1Synonyms: Voltage-gated potassium channel subunit Kv2.1
  5. Target

    Potassium voltage-gated channel subfamily B member 2

    go.drugbank.com/bio_entities/BE0004722
    TargetHumans

    Contributes to the delayed-rectifier voltage-gated potassium current in cortical pyramidal neurons and smooth muscle cells … Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and smooth muscle cells.

    Polypeptides: Potassium voltage-gated channel subfamily B member 2Synonyms: Voltage-gated potassium channel subunit Kv2.2
  6. Drug

    Paroxetine

    go.drugbank.com/drugs/DB00715
    ApprovedInvestigational

    Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil.

    Products: AS-PAROKS 20 MG FILM TABLET, 28 ADET, PAROXETINA DOC GENERICI
  7. Drug

    Witch hazel

    go.drugbank.com/drugs/DB11111
    ApprovedInvestigationalNutraceutical

    Products: Select Brand Hemorrhoid
  8. Drug

    Atorvastatin

    go.drugbank.com/drugs/DB01076
    ApprovedInvestigational

    [A181090,A181093,A181096,A181427,A181475,A181538] Statins were shown to reduce the incidences of all-cause mortality, including fatal and non-fatal CVD, as well as the need for surgical revascularization … is a critical metabolic reaction involved in the production of several compounds involved in lipid metabolism and transport, including cholesterol, low-density lipoprotein (LDL) (sometimes referred to as

    Products: AS-ATOKS 10 MG FILM KAPLI TABLET, 30 ADET, AS-ATOKS 20 MG FILM KAPLI TABLET, 30 ADET
  9. Target

    Potassium voltage-gated channel subfamily E member 1

    go.drugbank.com/bio_entities/BE0000489
    TargetHumans

    Ancillary protein that functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits

    Polypeptides: Potassium voltage-gated channel subfamily E member 1Synonyms: IKs producing slow voltage-gated potassium channel subunit beta Mink
  10. Target

    Potassium voltage-gated channel subfamily KQT member 1

    go.drugbank.com/bio_entities/BE0000672
    TargetHumans

    When associated with KCNE4, inhibits voltage-gated potassium channel activity (PubMed:19687231). … Also promotes a delayed voltage activated potassium current showing outward rectification characteristic (By similarity).

    Polypeptides: Potassium voltage-gated channel subfamily KQT member 1Synonyms: Voltage-gated potassium channel subunit Kv7.1, IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1