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Mifamurtide
go.drugbank.com/drugs/DB13615ApprovedInvestigationalAlso called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP). … While about 90% of patients with newly diagnosed osteosarcoma may achieve complete remission from first-line therapies, the prognosis is still poor for patients with non-metastatic osteosarcoma with lower
Beludavimab
go.drugbank.com/drugs/DB18952InvestigationalBeludavimab is under investigation in clinical trial NCT04746183 (AGILE (Early Phase Platform Trial for COVID-19)).
Synonyms: IMMUNOGLOBULIN G1 (246-ALANINE,340-LEUCINE,342-GLUTAMIC ACID,438-LEUCINE,444-SERINE), ANTI-(SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 SPIKE GLYCOPROTEIN RECEPTOR-BINDING DOMAIN) (HUMAN MONOCLONALAlanine
go.drugbank.com/drugs/DB00160ApprovedInvestigationalNutraceuticalIt is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and the central nervous system.
Mixtures: Aminosyn-PF, Aminosyn-PFDoxycycline
go.drugbank.com/drugs/DB00254ApprovedInvestigationalVet approvedDoxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. It is a second-generation tetracycline that was first discovered in 1967. Second-generation tetracyclines exhibit lesser toxicity than first-generatio...
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Doxycycline for Injection USP, Ligosan 140 mg/g Gel zur periodontalen AnwendungMAP kinase-interacting serine/threonine-protein kinase 2
go.drugbank.com/bio_entities/BE0009489TargetHumansMay play a role in the response to environmental stress and cytokines.
Polypeptides: MAP kinase-interacting serine/threonine-protein kinase 2Synonyms: MAP kinase signal-integrating kinase 2Biotin
go.drugbank.com/drugs/DB00121ApprovedInvestigationalNutraceuticalA water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Mixtures: Prenate Max, Doctor's Choice Brand for MenDrotaverine
go.drugbank.com/drugs/DB06751ApprovedWithdrawnIt is approved for use in Thailand as oral tablets or intramuscular injections.[L22689] … Drotaverine is an antispasmodic drug that works by inhibiting phosphodiesterase-4 (PDE4).
Categories: Drugs for Functional Gastrointestinal DisordersTadalafil
go.drugbank.com/drugs/DB00820ApprovedInvestigational[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. … In contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and a longer half-life which has made it a more suitable option for chronic once-daily dosing in the treatment
Categories: Antihypertensives for Pulmonary Arterial Hypertension, Cytochrome P-450 SubstratesProducts: Mar-tadalafilRucaparib
go.drugbank.com/drugs/DB12332ApprovedInvestigationalan androgen receptor–directed therapy, confirming clinical benefit for an indication that previously had accelerated approval. … [A249240] The drug was later approved by the European Commission in May 2018.[L42185] It is currently used to treat recurrent ovarian and prostate cancer in adults.[L42155,L42185].
Categories: Cytochrome P-450 CYP1A2 Inducers, P-glycoprotein inhibitorsThrombin
go.drugbank.com/drugs/DB11300ApprovedInvestigationalThis thrombosis may result from the development of antibodies against bovine thrombin [FDA Label]. Bleeding may result from the development of antibodies against bovine factor V [FDA Label]. … These antibodies may subsequently cross-react with endogenous human factor V and lead to its deficiency [FDA Label].
Mixtures: SAN. VE TİC. LTD., ARTISS - Lösungen für einen Gewebekleber