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Doxylamine
go.drugbank.com/drugs/DB00366ApprovedInvestigationalVet approvedIt is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.
Mixtures: PMS-doxylamine-pyridoxine, N - TimeSynonyms: N,N-Dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine, Phenyl-2-pyridylmethyl-beta-N,N-dimethylaminoethyl etherPropiolactone
go.drugbank.com/drugs/DB09348ApprovedWithdrawnPropiolactone was first commercially available in the United States in 1958.[A32144] … It has been used against bacteria, fungi, and virus.[A32144] It is currently FDA approved for its use as an indirect additive used in food contact substances.
Categories: Compounds used in a research, industrial, or household settingGallium nitrate
go.drugbank.com/drugs/DB05260ApprovedInvestigationalGallium nitrate is a nitrate salt of [DB14524], a heavy metal that has been used as a diagnostic agent.[A260816] Gallium nitrate is reported to possess antiresorptive and hypocalcemic effects on bone. … [L47726] Apart from cancer-related hypercalcemia, gallium nitrate has been studied in arthritis, autoimmune disorders, and tumours.[A260830]
Rose bengal
go.drugbank.com/drugs/DB11182ApprovedInvestigationalRose bengal is a pink stain derived as an analogue of fluorescein. Its disodium salt in ophthalmic solutions has been used as a diagnostic agent in suspected damage to conjunctival and corneal cells. … The clinical applications of rose bengal as injectable formulation under the name PV-10 in melanoma, breast cancer and skin conditions such as eczema and psoriasis are being investigated in clinical trials
Categories: Compounds used in a research, industrial, or household settingPhenoxyethanol
go.drugbank.com/drugs/DB11304ApprovedInvestigationalIt is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, and also as an anesthetic in fish aquaculture. … Phenoxyethanol has been classified as an antimicrobial and preservative by Health Canada [L2623].
Potassium Iodide
go.drugbank.com/drugs/DB06715ApprovedInvestigationalSaturated solution of Potassium Iodide (SSKI) is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperthyroidism (also known as thyroid storm or thyrotoxic crisis … SSKI can also be used for radioiodine-contamination emergencies or in preparation of thyrotoxic patients for thyroidectomy.
Mixtures: Ribotin-E, Vitamines Et MinerauxProcaine
go.drugbank.com/drugs/DB00721ApprovedInvestigationalVet approved(From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in treatment-experienced HIV patients [L1215]. … A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block.
Tangerine peel
go.drugbank.com/drugs/DB14316InvestigationalTangerine peel is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Chen PiInositol nicotinate
go.drugbank.com/drugs/DB08949ApprovedWithdrawnNicotinic acid plays an essential role in many important metabolic processes and has been used as lipid-lowering agent. … Niacin exists in different forms including nicotinic acid, nicotinamide and other derivatives such as inositol nicotinate.
Adagrasib
go.drugbank.com/drugs/DB15568ApprovedInvestigationalKRAS mutations are highly common in cancer and account for approximately 85% of all RAS family mutations. … The phase II of the same study showed that in patients with KRAS<sup>G12C</sup>-mutated non-small-cell lung cancer (NSCLC), adagrasib was efficient without new safety signals.
Categories: RAS GTPase Inhibitors