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Acalabrutinib
go.drugbank.com/drugs/DB11703ApprovedInvestigationalor/and that fill an unmet medical need based on a surrogate endpoint. … [L42795,L42800] Unlike Calquence capsules, the co-administration of Calquence tablets and PPIs does not have an effect in the pharmacokinetics of acalabrutinib.
Categories: Antineoplastic and Immunomodulating AgentsProducts: CALQUENCE® 100MG, CALQUENCE HARD CAPSULES 100MGCopper
go.drugbank.com/drugs/DB09130ApprovedInvestigationalCopper is a transition metal and a trace element in the body. It is important to the function of many enzymes including cytochrome c oxidase, monoamine oxidase and superoxide dismutase [FDA Label].
Mixtures: Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo, Zinc Chelate 20mg With Copper ChelateCategories: Diet, Food, and NutritionAzacitidine
go.drugbank.com/drugs/DB00928ApprovedInvestigationalAs an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and inhibiting protein and DNA synthesis. … [A1407] Due to its anti-neoplastic activity and its ability to inhibit methylation in replicating DNA, azacytidine has been used mainly used in the treatment of myelodysplastic syndromes (MDS) and acute
Categories: Antineoplastic and Immunomodulating Agents, Nucleic Acids, Nucleotides, and NucleosidesProducts: Vidaza powder for suspension for injection 100mg/vial, AZADINE POWDER FOR SUSPENSION FOR INJECTION 100MG/VIALPrilocaine
go.drugbank.com/drugs/DB00750ApprovedInvestigationalA local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Mixtures: LOKARIL % 5 KREM ,10G, PRESTIGE® NFSynonyms: alpha-n-Propylamino-2-methylpropionanilide, N-(2-Methylphenyl)-2-(propylamino)propanamideSatralizumab
go.drugbank.com/drugs/DB15762ApprovedInvestigational[A218551] It received subsequent approvals in Switzerland and Japan,[A218551] and was approved for use by the FDA in August 2020,[L15566] becoming the 3rd treatment to receive FDA approval for NMOSD (after … [A218546,A218551] Satralizumab is thought to exert its therapeutic benefits by blocking IL-6 receptors and, subsequently, these inflammatory responses.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: ENSPRYNG® SATRALIZUMAB 120MG/ML, ENSPRYNG SOLUTION FOR INJECTION IN PREFILLED SYRINGE 120MG/1MLAsciminib
go.drugbank.com/drugs/DB12597ApprovedInvestigational[A241065] Asciminib is unique in that it acts as an allosteric inhibitor, binding at the myristoyl pocket of the BCR-ABL1 protein and locking it into an inactive conformation. … Existing inhibitors of ABL compete at the ATP binding sites of these proteins and can be classified into those that target the active conformation of the kinase domain ([dasatinib], [bosutinib]) and those
Categories: Antineoplastic and Immunomodulating AgentsProducts: Scemblix 20mg film-coated tablet, Scemblix 40mg film-coated tabletGuselkumab
go.drugbank.com/drugs/DB11834ApprovedInvestigationalDeveloped by Janssen, the subcutenous injection form of guselkumab was approved in July 2017 under the market name Tremfya for the treatment of adult patients with moderate-to-severe plaque psoriasis. … IL-23 is an inflammatory cytokine that activates the CD4+ T-helper (Th17) cell pathway to mediate the inflammatory cascade that induces psoriatic plaque formation [A20357].
Categories: Amino Acids, Peptides, and Proteins, Skin and Mucous Membrane AgentsProducts: TREMFYA 100MG/ML SOLUTION FOR INJECTION, Tremfya One-Press 100mg/ml Solution for InjectionAcetylcysteine
go.drugbank.com/drugs/DB06151ApprovedInvestigationalAcetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of [acetaminophen] overdose. … [A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.[L31488]
Mixtures: Levomefolate Calcium Acetylcysteine and Mecobalamin Algal, Levomefolate Calcium, Acetylcysteine, Mecobalamin and AlgalCategories: Cough and Cold Preparations, Amino Acids, Peptides, and ProteinsOrlistat
go.drugbank.com/drugs/DB01083ApprovedInvestigationalObesity-related complications lead to significant personal and economic burden by reducing quality of life and increasing the cost of healthcare. … [L11130] This drug is a generally well-tolerated and effective weight-loss aid and is now available in both over-the-counter[L31963] and prescription preparations, depending on the dosage quantity.
Categories: Alimentary Tract and MetabolismProducts: ORLISTAT 120MG, XENICAL CAPSULE 120MGEconazole
go.drugbank.com/drugs/DB01127ApprovedIt is used topically in dermatomycoses also orally and parenterally.
Categories: Imidazole and Triazole Derivatives, Genito Urinary System and Sex HormonesProducts: GYNO-PEVARYL DEPOT 150MG, Ecostatin Vaginal Ovule 150mg