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Nepafenac
go.drugbank.com/drugs/DB06802ApprovedInvestigationalNepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.
Categories: Selective Cyclooxygenase 2 Inhibitors (NSAIDs), Anti-Inflammatory Agents, Non-Steroidal (Non-Selective)Synonyms: 2-amino-3-benzoylbenzeneacetamideGentamicin
go.drugbank.com/drugs/DB00798ApprovedInvestigationalVet approved[A234364] This synergistic activity is not only important for the treatment of complex infections, but can also contribute to dose optimization and reduced adverse effects. … [A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment of severe gram-negative infections including those caused by
Mixtures: QUADRIDERM NF, Gentamicin Sulfate In Nacl O.9% InjCategories: OCT2 Substrates with a Narrow Therapeutic Index, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexTerpin hydrate
go.drugbank.com/drugs/DB13163ApprovedWithdrawnElixirs of terpin hydrate are still available to patients as prescription medications to be prepared by specialty compounding pharmacies. … It was popular in the United States since the late nineteenth century, but was removed from marketed medications in the 1990s after FDA stated that "based on evidence currently available, there are inadequate
Mixtures: .-2 เอ็กซ์เพ็คท์Synonyms: cis-p-methane-1,8-diol monohydrateTozinameran
go.drugbank.com/drugs/DB15696ApprovedInvestigational[A225386] Comirnaty was granted a EUA in the UK on December 2, 2020,[L26676] and in Canada on December 9, 2020[L26671] for active immunization against SARS-CoV-2. … [L15017, L15022] Comirnaty received fast track designation by the U.S. FDA on July 13, 2020.
Mixtures: Comirnaty Original & Omicron Ba.4/ba.5, Comirnaty Original & Omicron Ba.4/ba.5Bicalutamide
go.drugbank.com/drugs/DB01128ApprovedInvestigationalBicalutamide is an oral non-steroidal anti-androgen for prostate cancer. It is comprised of a racemic mixture that is a 50:50 composition of the (R)-bicalutamide and (S)-bicalutamide enantionmers. … Bicalutamide binds to the androgen receptor.
Categories: Antiandrogens, non-steroidal, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: Nu-bicalutamide, Van-bicalutamideAmivantamab
go.drugbank.com/drugs/DB16695ApprovedInvestigational[A235133] Amivantamab was granted FDA approval on 21 May 2021,[L34193] followed by the approval by the EMA on 9 December 2021 [L41474] and Health Canada on 30 March 2022. … non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertion mutations, as detected by an FDA-approved test, whose disease has progressed on or after platinum-based
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
go.drugbank.com/bio_entities/BE0000224TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Synonyms: Complex I-MWFENADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10
go.drugbank.com/bio_entities/BE0000245TargetHumansAccessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. … Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain
Synonyms: Complex I-PDSWNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
go.drugbank.com/bio_entities/BE0000284TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Synonyms: Complex I-B12NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial
go.drugbank.com/bio_entities/BE0000313TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Synonyms: Complex I-KFYI