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Displaying results 1141 - 1150 of 10000 in total
  1. Drug

    Allyl-{4-[3-(4-Bromo-Phenyl)-Benzofuran-6-Yloxy]-but-2-Enyl}-Methyl-Amine

    go.drugbank.com/drugs/DB03771
    Experimental

  2. Target

    CD44 antigen

    go.drugbank.com/bio_entities/BE0001113
    TargetHumans

    Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment (PubMed:16541107, PubMed:19703720, PubMed:22726066). Participates...

    Synonyms: PGP-I, HUTCH-I
  3. Drug

    Ecamsule

    go.drugbank.com/drugs/DB09534
    Approved

    Ecamsule is an organic compound which is added to many sunscreens to filter out UVA rays. It is a benzylidene camphor derivative, many of which are known for their excellent photostability. … Ecamsule has been approved for use in the U.S. since 2006, but only at a specific concentration and only in a few products manufactured by L'Oreal.

    Mixtures: Thermal S Uv SPF 20, Anthelios XL Melt-IN CreamCategories: Compounds used in a research, industrial, or household setting
  4. Drug

    Calcium glycerophosphate

    go.drugbank.com/drugs/DB11264
    Approved

    It is also present in dental or oral hygiene products due to its cariostatic effects. … By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source of calcium or phosphorus), or in food products such as gelatins, puddings

    Mixtures: Alsimine W Vitamins A D, Somarexin and C 1000Synonyms: calcium β-glycerophosphate, β-glycerophosphoric acid calcium salt
  5. Drug

    Axicabtagene ciloleucel

    go.drugbank.com/drugs/DB13915
    ApprovedInvestigational

    Axicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. … [L40054] The development of resulted from early preclinical studies conducted by a group of researchers at the National Cancer Institute (NCI), who demonstrated that T cells expressing an anti-CD19 CAR

    Categories: Antigens, Differentiation, B-Lymphocyte, Genetically-modified Autologous T CellsSynonyms: Autologous T cells transduced with retroviral vector encoding an anti-CD-19 CD28/CD3-zeta chimeric antigen receptor
  6. Target

    Corrinoid adenosyltransferase MMAB

    go.drugbank.com/bio_entities/BE0000456
    EnzymeHumans

    Converts cob(I)alamin to adenosylcobalamin (adenosylcob(III)alamin), a coenzyme for methylmalonyl-CoA mutase, therefore participates in the final step of the vitamin B12 conversion (PubMed:12514191).

    Synonyms: ATP:co(I)rrinoid adenosyltransferase MMAB
  7. Target

    Inosine-5'-monophosphate dehydrogenase 1

    go.drugbank.com/bio_entities/BE0000761
    TargetEnzymeHumans

    Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation ...

    Synonyms: IMPDH-I
  8. Target

    Glutamine synthetase

    go.drugbank.com/bio_entities/BE0001881
    TargetSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

    Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

    Synonyms: Glutamine synthetase I beta
  9. Target

    N-formyl peptide receptor 2

    go.drugbank.com/bio_entities/BE0012843
    TargetHumans

    In addition, can recognize a variety of chemically distinct endogenous ligands including proteins and lipids besides formylpeptides and thereby plays multiple roles in inflammation. … Ligand binding causes a conformation change that triggers signaling via G(i)/GNAI1 inhibiting adenylate cyclase activity, leading to decreased intracellular cAMP levels (PubMed:40080544).

    Synonyms: FMLP-R-I, FMLP-related receptor I
  10. Drug

    Opium

    go.drugbank.com/drugs/DB11130
    ApprovedIllicit

    This plant is an integrant of the Papaveraceae family, and it is characterized by solitary leaves and capsulated fruits. … During the years, opium was used as a sedative and hypnotic, but it was determined to be addictive.[A32171] Opium is extracted from _Papaver somniferum_, which is more known as poppies.

    Mixtures: Diban Cap, Diban CapCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 Substrates