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Displaying results 1151 - 1160 of 10000 in total
  1. Drug

    Terlipressin

    go.drugbank.com/drugs/DB02638
    ApprovedInvestigational

    Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor.[A2601] It is a prodrug of [lypressin], or lysine vasopressin. … [L43217] As a potent vasopressor, terlipressin has been investigated in various shock states and conditions with diminished vasomotor tone.

    Products: TERLIPRESSINA SUN, HAEMOPRESSIN® 1 MG
  2. Target

    Transient receptor potential cation channel subfamily A member 1

    go.drugbank.com/bio_entities/BE0001122
    TargetHumans

    Has a central role in the pain response to endogenous inflammatory mediators, such as bradykinin and to a diverse array of irritants. … Has a relatively high Ca(2+) selectivity, with a preference for divalent over monovalent cations (Ca(2+) > Ba(2+) > Mg(2+) > NH4(+) > Li(+) > K(+)), the influx of cation into the cytoplasm leads to membrane

    Polypeptides: Transient receptor potential cation channel subfamily A member 1
  3. Target

    Low affinity immunoglobulin gamma Fc region receptor III-A

    go.drugbank.com/bio_entities/BE0002097
    TargetHumans

    Optimally activated upon binding of clustered antigen-IgG complexes displayed on cell surfaces, triggers lysis of antibody-coated cells, a process known as antibody-dependent cellular cytotoxicity (ADCC

    Polypeptides: Low affinity immunoglobulin gamma Fc region receptor III-ASynonyms: IgG Fc receptor III-A
  4. Drug

    Teriparatide

    go.drugbank.com/drugs/DB06285
    ApprovedInvestigational

    Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent.[A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. … [A251395] First approved in the United States in November 2002 and in Europe in April 2003,[A251400] teriparatide makes the first approved drug in a new category of osteoporosis therapy called anabolic

    Synonyms: PTH 1-34, PTH (1-34)Products: Teriparatide Sun, TEOTIDE®
  5. Drug

    Benzocaine

    go.drugbank.com/drugs/DB01086
    ApprovedInvestigational

    Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. … [A231219] It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.[A231259]

    Mixtures: Kank-A, Blistex Kank-ACategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  6. Drug

    Zinc gluconate

    go.drugbank.com/drugs/DB11248
    ApprovedInvestigationalVet approved

    It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration of common colds and with decreased symptom severity. … Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA [L2081].

    Mixtures: A+ Zinc Tab, Evc Liquid Vitamins A,c,b6 With Beta Caro&znProducts: ZINC INJECTABLE A 1mg/ml, solution injectable pour perfusion, Zink Aguettant 1 mg/ml Konzentrat zur Herstellung einer Infusionslösung
  7. Target

    Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial

    go.drugbank.com/bio_entities/BE0002256
    TargetEnzymeHumans

    ) and produce a new acyl-CoA. … Catalyzes the first, rate-limiting step of ketone body utilization in extrahepatic tissues, by transferring coenzyme A (CoA) from a donor thiolester species (succinyl-CoA) to an acceptor carboxylate (acetoacetate

    Polypeptides: Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
  8. Target

    NKG2-A/NKG2-B type II integral membrane protein

    go.drugbank.com/bio_entities/BE0010560
    TargetHumans

    Dominantly counteracts T cell receptor signaling on a subset of memory/effector CD8-positive T cells as part of an antigen-driven response to avoid autoimmunity (PubMed:12387742). … In HLA-E-rich tumor microenvironment, acts as an immune inhibitory checkpoint and may contribute to progressive loss of effector functions of NK cells and tumor-specific T cells, a state known as cell

    Polypeptides: NKG2-A/NKG2-B type II integral membrane proteinSynonyms: NK cell receptor A, NKG2-A/B-activating NK receptor
  9. Drug

    Triprolidine

    go.drugbank.com/drugs/DB00427
    Approved

    First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of cough and cold medicines. It may cause drowsiness.

    Mixtures: Ed-A-hist Pse, A-FERIN DECO ŞURUP, 100 MLCategories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Technetium Tc-99m etifenin

    go.drugbank.com/drugs/DB13183
    Investigational

    Products: EHIDA KIT PARA LA PREPARACIÓN DE RADIOFÁRMACOS.