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Butenafine
go.drugbank.com/drugs/DB01091ApprovedButenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols. … In particular, butenafine acts to inhibit the activity of the squalene epoxidase enzyme that is essential in the formation of sterols necessary for fungal cell membranes.
Synonyms: (4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine, N-(p-tert-butylbenzyl)-N-methyl-1-naphthalenemethylamineProducts: Tinactin Once-A-day Cream, BUTEFIN %1 KREM, 15 GCyclophosphamide
go.drugbank.com/drugs/DB00531ApprovedInvestigationalPrecursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. … It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep.
Categories: Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic IndexSynonyms: N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide, 2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxideFilgrastim
go.drugbank.com/drugs/DB00099ApprovedInvestigational[L40714] Human G-CSF is a glycoprotein that regulates the production and release of neutrophils from the bone marrow. … [L40773] A long-acting, pegylated G-CSF, [pegfilgrastim], was made available to increase the duration of action of the drug.
Synonyms: r-metHuG-CSFInternational brands: White-CTrolamine salicylate
go.drugbank.com/drugs/DB11079ApprovedAs with other salicylates, trolamine salicylate is an inhibitor of cyclo-oxygenase (COX) enzymes with no reported selectivity towards a specific enzyme isoform. … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid.
Categories: Non COX-2 selective NSAIDSProducts: Antiphlogistine Rub A-535 No Odour Fmla Ont, Dr Joe lab ARTHRITIS EXTRA STRENGTHNot a candidate for curative surgery or radiation
go.drugbank.com/conditions/DBCOND0144324Synonyms: Not a candidate for curative surgery or radiationNot a candidate for surgery or definitive chemoradiation
go.drugbank.com/conditions/DBCOND0144291Synonyms: Not a candidate for surgery or definitive chemoradiationPatients at High-Risk of a Cardiovascular Event
go.drugbank.com/conditions/DBCOND0163212Drugs: Bempedoic acidSynonyms: Patients at High-Risk of a Cardiovascular EventPrevious treatment with bevacizumab, oxaliplatin, and a fluoropyrimidine
go.drugbank.com/conditions/DBCOND0146852Drugs: RamucirumabSynonyms: Previous treatment with bevacizumab, oxaliplatin, and a fluoropyrimidineProphylaxis of perioperative bleeding caused by Hemophilia A
go.drugbank.com/conditions/DBCOND0089516Synonyms: Prophylaxis of perioperative bleeding caused by Hemophilia ALormetazepam
go.drugbank.com/drugs/DB13872ApprovedLormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia [L927]. … It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 7-Chloro-1,3-dihydro-5-(o-chlorophenyl)-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one, 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one