Search
Vericiguat
go.drugbank.com/drugs/DB15456ApprovedInvestigationalcell types) that catalyze the synthesis of cyclic guanosine monophosphate (cGMP) in response to activation by nitric oxide (NO). … [L31178] Vericiguat was approved by the FDA in January 2021 - developed by Merck under the brand name Verquvo - for use in certain patients with systolic heart failure.
Products: VERQUVO 10 MG FİLM KAPLI TABLET , 14 ADET, VERQUVO 10 MG FİLM KAPLI TABLET , 28 ADETOmega-3 fatty acids
go.drugbank.com/drugs/DB11133ApprovedInvestigationalNutraceuticalFood and Drug Administration gave "qualified health claim" status to EPA and DHA omega-3 fatty acids. … α-linolenic acid (ALA) (found in plant oils), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) (both commonly found in fish oil that originally come from microalgae that is further consumed by
Mixtures: LIPOMEGA® 10, Lipidem 200mg/ml Emulsion for InfusionProducts: EPAX720 MG, GNC Fish Body Oil 1000Pioglitazone
go.drugbank.com/drugs/DB01132ApprovedInvestigational[A19757] PPARs are ligand-activated transcription factors that are involved in the expression of more than 100 genes and affect numerous metabolic processes, most notably lipid and glucose homeostasis. … Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus.
Synonyms: 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione, (±)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedioneMixtures: DROPIA-MET 15/500 MG FILM KAPLI TABLET, 180 ADET, GLIFIX PLUS 15 MG/1000 MG FILM KAPLI TABLET ,TABLET, 60 ADETDiethylstilbestrol
go.drugbank.com/drugs/DB00255ApprovedWithdrawnAccording to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsProducts: Stilbestrol Tablets 1.0 mg, Stilbestrol Tablets 0.1 mgIvabradine
go.drugbank.com/drugs/DB09083ApprovedInvestigational≥70 beats per minute, who are not on beta-blockers due to contraindications or already receiving maximum beta-blocker dose. … Ivabradine acts by selectively inhibiting the "funny" channel pacemaker current (If) in the sinoatrial node in a dose-dependent fashion, resulting in a lower heart rate and thus more blood to flow to the
Mixtures: Implicor 50 mg/5 mg Filmtabletten, IMPLICOR FILM-COATED TABLET 50 mg/5 mgCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMianserin
go.drugbank.com/drugs/DB06148ApprovedWithdrawnA tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of mirtazapine.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin 5-HT2 Receptor AntagonistsProducts: MIANSERIN-NEURAX 10 MG, TOLVON TABLET 10 MG, 30 ADETValdecoxib
go.drugbank.com/drugs/DB00580ApprovedWithdrawnValdecoxib was removed from the Canadian, U.S., and E.U. markets in 2005 due to concerns about a possible increased risk of heart attack and stroke.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: BEXTRA ® 10 MG TABLETAS RECUBIERTAS, VALDYNE 40 MG TABLETAS RECUBIERTASClofarabine
go.drugbank.com/drugs/DB00631ApprovedInvestigationalClofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed.
Synonyms: (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-olProducts: EVORABIN 1MG/1ML İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 60 ADET, EVOLTU 20 MG/ 20 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE , 1 ADETBenzatropine
go.drugbank.com/drugs/DB00245ApprovedInvestigationalIt is a combination molecule between a tropane ring, similar to cocaine, and a diphenyl ether from the dialkylpiperazines determined to be a dopamine uptake inhibitor since 1970. … [A37914] Benztropine was developed by USL Pharma and officially approved by the FDA on 1996.[L5500]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: COGENTIN INJECTION 2 mg/2 ml, APO-BENZTROPINE TABLET 2 mgProchlorperazine
go.drugbank.com/drugs/DB00433ApprovedInvestigationalVet approved[label] It mainly works by depressing the chemoreceptor trigger zone and blocking D2 dopamine receptors in the brain. It was shown to also block histaminergic, cholinergic and noradrenergic receptors. … Although newer antiemetic agents such as 5-HT3 antagonists are more heavily promoted, prochlorperazine is still widely used in nausea and vomiting.[L6640]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine, 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine