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Displaying results 1171 - 1180 of 10000 in total
  1. Drug

    Aminobenzoic acid

    go.drugbank.com/drugs/DB02362
    ApprovedWithdrawn

    A member of the vitamin B complex. It used to be common in sunscreening agents until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.

    Mixtures: KORDEL`S NUTRITIME TABLET, Multi B Complex Plus 500mg Vitamin C TabletsCategories: 4-Aminobenzoic Acid, Vitamin B Complex
  2. Pathway

    Azathioprine Action Pathway

    smpdb.ca/view/SMP0000427
    Drug action

    Azathioprine is a purine antimetabolite prodrug that exerts cytotoxic effects via three mechanisms: via incorporation of thiodeoxyguanosine triphosphate into DNA and thioguanosine triphosphate into RNA, inhibition of de novo synthesis of...

    Drugs: Tetrahydrofolic acid · Ademetionine · Aspartic acid · L-Glutamine · Adenosine phosphate · Glutamic acid +27 more
    Enzymes: Thiopurine S-methyltransferase
  3. Pathway

    Mercaptopurine Action Pathway

    smpdb.ca/view/SMP0000428
    Drug action

    Mercaptopurine is a purine antimetabolite prodrug that exerts cytotoxic effects via three mechanisms: via incorporation of thiodeoxyguanosine triphosphate into DNA and thioguanosine triphosphate into RNA, inhibition of de novo synthesis ...

    Drugs: Tetrahydrofolic acid · Ademetionine · Aspartic acid · L-Glutamine · Adenosine phosphate · Glutamic acid +26 more
    Enzymes: Thiopurine S-methyltransferase
  4. Drug

    Metoprolol

    go.drugbank.com/drugs/DB00264
    ApprovedInvestigational

    Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release. … [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US.

    Mixtures: METOPROLOL HCT S 100/12.5, METOPROLOL HCT S 100/12.5Categories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor Antagonists
  5. Pathway

    Thioguanine Action Pathway (old)

    smpdb.ca/view/SMP0000430
    Drug action

    Thioguanine is a purine antimetabolite prodrug closely related to mercaptopurine and similarly inhibits purine metabolism. The thioguanine pathway is shown as a part of the mercaptopurine pathway. Thioguanine exerts cytotoxic effects via...

    Drugs: Tetrahydrofolic acid · Ademetionine · Aspartic acid · L-Glutamine · Adenosine phosphate · Glutamic acid +27 more
    Enzymes: Thiopurine S-methyltransferase
  6. Drug

    Rice bran

    go.drugbank.com/drugs/DB14361
    Approved

    Rice bran is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Mixtures: Ari S-Liner
  7. Drug

    Bisacodyl

    go.drugbank.com/drugs/DB09020
    ApprovedInvestigational

    Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation. … [A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a laxative since 1952.[A233300]

    Mixtures: Gentlax S, BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADETSynonyms: Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester)
  8. Drug

    Foreskin fibroblast (neonatal)

    go.drugbank.com/drugs/DB10770
    Approved

    Dermagraft has been combined with [DB10772] to create a drug beneficial to patients with open burn wounds [L2427]. … Also known as Dermagraft, this device is a cryopreserved human fibroblast-derived dermal substitute.

  9. Drug

    Susoctocog alfa

    go.drugbank.com/drugs/DB11606
    ApprovedInvestigational

    In a global, prospective, controlled, multi-center Phase 2/3 open-label clinical trial, all patients responded to susoctocog alfa treatment within 24 hours [L1129]. … Susoctocog alfa is a glycoprotein containing a 90 kDa heavy chain and a 80 kDa light chain with the naturally-occuring B domain replaced with a twenty-four amino acid linker.

    Synonyms: Porcine recombinant factor VIII B-domain truncated, Antihemophilic factor porcine, B-domain truncated recombinant
  10. Drug

    Clavulanic acid

    go.drugbank.com/drugs/DB00766
    ApprovedInvestigationalVet approved

    [A182228]When it is combined with amoxicillin, clavulanic acid is frequently known as Augmentin, Co-Amoxiclav, or Clavulin.[L7880,L7904,L7910] … Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with [Amoxicillin] or [Ticarcillin] to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening

    Mixtures: CLAMOXIN S, AMOXICILLINA E ACIDO CLAVULANICO SANDOZ A/SCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring