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Displaying results 1181 - 1190 of 10000 in total
  1. Drug

    Dactylis glomerata pollen

    go.drugbank.com/drugs/DB10379
    Approved

    Dactylis glomerata pollen is the pollen of the Dactylis glomerata plant. Dactylis glomerata pollen is mainly used in allergenic testing.

    Mixtures: GRASS MIX Number 4-S, GRASS MIX Number 4-SCategories: Grass Pollen Allergen Extracts
  2. Pathway

    Gs Serotonergic Smooth Muscle Contraction

    smpdb.ca/view/SMP0127045
    Physiological

    Serotonergic (5-HT4) receptors are typically coupled to Gs proteins. Activation of Gs proteins stimulates adenylate cyclase (AC), leading to increased production of cyclic AMP (cAMP) from ATP.Gs proteins stimulate adenylate cyclase (AC) ...

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Pyrophosphoric acid
    Enzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
  3. Drug

    Flax seed

    go.drugbank.com/drugs/DB10708
    Approved

    Flax seed allergenic extract is used in allergenic testing.

    Mixtures: Nature"s Gift CoQ10 Plus
  4. Pathway

    Gi Serotonergic Smooth Muscle Relaxation

    smpdb.ca/view/SMP0126986
    Physiological

    Serotonin increases the motility of the GI tract muscles, induces muscle constriction in the lungs and uterus, influences vessel muscles in both directions (constriction/relaxation), takes part in platelet

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Pyrophosphoric acid
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  5. Pathway

    Metoclopramide Serotonergic Smooth Muscle Contraction

    smpdb.ca/view/SMP0127039
    Drug action

    Metoclopramide's agonism of 5-HT4 receptors in the gastrointestinal tract can stimulate gastrointestinal motility, including enhancing gastric emptying and promoting peristalsis. … Metoclopramide is a dopamine receptor antagonist and has been approved by the FDA to treat nausea and vomiting in patients with gastroesophageal reflux disease or diabetic gastroparesis by increasing gastric motility

    Drugs: ATP · Metoclopramide · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate +1 more
    Enzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
  6. Pathway

    Prucalopride Action Pathway

    smpdb.ca/view/SMP0127044
    Drug action

    Hence, prucalopride stimulates motility by interacting specifically with 5-HT4 receptors in the GI tract which causes a release of acetylcholine and further contraction of the muscle layer of the colon

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Pyrophosphoric acid +1 more
    Enzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
  7. Drug

    Rutin

    go.drugbank.com/drugs/DB01698
    ApprovedInvestigational

    A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.

    Synonyms: 3-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one, Vitamin PMixtures: KORDEL`S C TIME ACID FREE C 1000MG TABLET, KORDEL`S NUTRITIME TABLET
  8. Target

    CD9 antigen

    go.drugbank.com/bio_entities/BE0003377
    TargetHumans

    Involved in cell adhesion, cell motility and tumor metastasis (PubMed:7511626, PubMed:8478605)

    Synonyms: Motility-related protein
  9. Drug

    Trimebutine

    go.drugbank.com/drugs/DB09089
    ApprovedInvestigational

    Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects. … It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI disorders [A19691].

    Synonyms: 2-Dimethylamino-2-phenylbutyl 3,4,5-trimethoxybenzoatInternational brands: Newbutin SR
  10. Drug

    Sodium acetate

    go.drugbank.com/drugs/DB09395
    ApprovedInvestigational

    Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. … Medically, sodium acetate is important component as an electrolyte replenisher when given intravenously. It is mainly indicated to correct sodium levels in hyponatremic patients.

    Synonyms: Acetic acid, sodium salt (1:1)Mixtures: B S S STERILE IRRIGATING SOLUTION, Isolyte S