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Displaying results 1181 - 1190 of 6949 in total
  1. Target

    Interleukin-1 receptor-like 1

    go.drugbank.com/bio_entities/BE0013861
    TargetHumans

    Receptor for interleukin-33 (IL-33) which plays crucial roles in innate and adaptive immunity, contributing to tissue homeostasis and responses to environmental stresses together with coreceptor IL1RAP

    Polypeptides: Interleukin-1 receptor-like 1Function: cytokine receptor activity
  2. Target

    Interleukin-10 receptor subunit beta

    go.drugbank.com/bio_entities/BE0014312
    TargetHumans

    Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. … The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity.

    Polypeptides: Interleukin-10 receptor subunit betaSynonyms: IL-10 receptor subunit beta, Cytokine receptor class-II member 4
  3. Target

    TNF receptor-associated factor 6

    go.drugbank.com/bio_entities/BE0021309
    TargetHumans

    Adapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor (PubMed:12140561, PubMed:19825828, PubMed:8837778).

    Polypeptides: TNF receptor-associated factor 6
  4. Target

    G protein-coupled receptor 6

    go.drugbank.com/bio_entities/BE0021832
    TargetHumans

    Constitutively active G protein-coupled receptor that maintains high cAMP levels and contributes to several processes including neuronal development, through activation of intracellular signaling pathways

    Polypeptides: G protein-coupled receptor 6Synonyms: Sphingosine 1-phosphate receptor GPR6
  5. Drug

    Pantothenic acid

    go.drugbank.com/drugs/DB01783
    ApprovedInvestigationalNutraceuticalVet approved

    For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats.

    Mixtures: Se-Tan PLUS, For-2Categories: Preparations for Treatment of Wounds and Ulcers
  6. Drug

    Histidine

    go.drugbank.com/drugs/DB00117
    ApprovedInvestigationalNutraceutical

    An essential amino acid that is required for the production of histamine.

    Mixtures: GLAMIN SOLUTION FOR INFUSION, KABIVEN EMULSION FOR INFUSION
  7. Drug

    Pepsin

    go.drugbank.com/drugs/DB13198
    ApprovedWithdrawn

    Interestingly, recent research has suggested that pepsin participates in the digestion of nucleic acids [L2391]. … Pepsin is often used as a replacement enzyme for those with pancreatic insufficiency [L2357].

  8. Drug

    Medium-chain triglycerides

    go.drugbank.com/drugs/DB13959
    ApprovedInvestigational

    Medium-chain triglycerides (MCTs) are triglycerides made up of a glycerol backbone and three fatty acids with an aliphatic tail of six to 12 carbon atoms. MCTs are found in natural foods, such as coconut oil, palm kernel oil, and raw coc...

    Mixtures: OMEGA PLUS EMULSION FOR INFUSION, SmofKabiven Emulsion for InfusionCategories: Solutions for Parenteral Nutrition
  9. Target

    Prostaglandin E2 receptor EP1 subtype

    go.drugbank.com/bio_entities/BE0000064
    TargetHumans

    Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system.

    Polypeptides: Prostaglandin E2 receptor EP1 subtypeSynonyms: PGE receptor EP1 subtype, Prostanoid EP1 receptor
  10. Target

    Retinoic acid receptor RXR-beta

    go.drugbank.com/bio_entities/BE0000078
    TargetHumans

    Receptor for retinoic acid.

    Polypeptides: Retinoic acid receptor RXR-betaSynonyms: Retinoid X receptor beta, Nuclear receptor subfamily 2 group B member 2