Prostaglandin E2 receptor EP1 subtype

BE0000064ProteinHumansPTGER1

Receptor for prostaglandin E2 (PGE2). It is acted on by 19 drugs in DrugBank.

Gene name
PTGER1
UniProtKB entry
P34995Swiss-Prot
Cellular location
Cell membrane
Residues / weight
402 residues · 41,801 Da
Also known as
PGE receptor EP1 subtype · PGE2 receptor EP1 subtype · Prostanoid EP1 receptor

Resolves to

Protein
UniProtP34995UniProt namePE2R1_HUMAN
Gene
HGNCHGNC:9593NCBI Gene5731GenBank410209GeneCardsPTGER1
Pharmacology
IUPHAR/GtoPdb340KEGGhsa:5731
Structure
PDB9M1H
Drugs

What you can answer from here — as of September 07, 2019

19DrugsApproved to experimental, with action, bond type and pharmacological action
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15GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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49+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Prostaglandin E2 receptor EP1 subtype, how selective are they, and which programs against it are still in active trials?

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