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Displaying results 111 - 120 of 134099 in total
  1. Pathway

    Acylcarnitine 13-(3-methyl-5-pentylfuran-2-yl)tridecanoylcarnitine

    smpdb.ca/view/SMP0123471
    Metabolic

    This reaction can occur in both directions, and L-acetylcarnitine and CoA can react to form acetyl-CoA and L-carnitine in certain circumstances. … methyl-5-pentylfuran-2-yl)tridecanoyl-CoA and L-carnitine. 13-(3-methyl-5-pentylfuran-2-yl)tridecanoyl-CoA then enters into the mitochondrial beta-oxidation pathway to form aceytl-CoA.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  2. Pathway

    Acylcarnitine 9-(3-methyl-5-propylfuran-2-yl)nonanoylcarnitine

    smpdb.ca/view/SMP0123490
    Metabolic

    This reaction can occur in both directions, and L-acetylcarnitine and CoA can react to form acetyl-CoA and L-carnitine in certain circumstances. … 9-(3-methyl-5-propylfuran-2-yl)nonanoylcarnitine is an acylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  3. Pathway

    Acylcarnitine 15-(3-methyl-5-pentylfuran-2-yl)pentadecanoylcarnitine

    smpdb.ca/view/SMP0123507
    Metabolic

    This reaction can occur in both directions, and L-acetylcarnitine and CoA can react to form acetyl-CoA and L-carnitine in certain circumstances. … 3-methyl-5-pentylfuran-2-yl)pentadecanoyl-CoA and L-carnitine. 15-(3-methyl-5-pentylfuran-2-yl)pentadecanoyl-CoA then enters into the mitochondrial beta-oxidation pathway to form aceytl-CoA.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  4. Pathway

    Acylcarnitine 5-(3-methyl-5-pentylfuran-2-yl)pentanoylcarnitine

    smpdb.ca/view/SMP0123511
    Metabolic

    This reaction can occur in both directions, and L-acetylcarnitine and CoA can react to form acetyl-CoA and L-carnitine in certain circumstances. … 5-(3-methyl-5-pentylfuran-2-yl)pentanoylcarnitine is an acylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  5. Pathway

    Acylcarnitine 7-(3-methyl-5-pentylfuran-2-yl)heptanoylcarnitine

    smpdb.ca/view/SMP0123520
    Metabolic

    This reaction can occur in both directions, and L-acetylcarnitine and CoA can react to form acetyl-CoA and L-carnitine in certain circumstances. … 7-(3-methyl-5-pentylfuran-2-yl)heptanoylcarnitine is an acylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  6. Pathway

    Acylcarnitine 11-(3-methyl-5-pentylfuran-2-yl)undecanoylcarnitine

    smpdb.ca/view/SMP0123572
    Metabolic

    This reaction can occur in both directions, and L-acetylcarnitine and CoA can react to form acetyl-CoA and L-carnitine in certain circumstances. … 11-(3-methyl-5-pentylfuran-2-yl)undecanoylcarnitine is an acylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  7. Pathway

    Peginterferon alfa-2a Action Pathway

    smpdb.ca/view/SMP0125981
    Drug action

    Peginterferon alfa-2a activate interferon alpha receptors 1 and 2 (IFNAR1 and IFNAR2) which are associated with tyrosine kinase 2 (TYK2) and JAK1 respectively. … They act through IKKa and IKKb to drive NFKB induction of genes associated with survival signals, antigen processing and presentation, and proliferation.

    Drugs: Peginterferon alfa-2a
    Enzymes: Signal transducer and activator of transcription 3, Signal transducer and activator of transcription 2
  8. Pathway

    Peginterferon alfa-2b Action Pathway

    smpdb.ca/view/SMP0126026
    Drug action

    Its immunomodulatory effects are the enhancement of the phagocytic activity, the activation of NK cells, the stimulation of cytotoxic T-lymphocytes, and the upregulation of the Th1 T-helper cell subset … It is also used as an adjuvant treatment of melanoma with microscopic or gross nodal involvement within 84 days of definitive surgical resection.

    Drugs: Peginterferon alfa-2b
    Enzymes: Signal transducer and activator of transcription 3, Signal transducer and activator of transcription 2
  9. Pathway

    Interferon beta-1a Action Pathway

    smpdb.ca/view/SMP0126027
    Drug action

    They act through IKKa and IKKb to drive NFKB induction of genes associated with survival signals, antigen processing and presentation, and proliferation. … These transphosphorylate themselves and phosphorylate the IFNAR and IFNAR2c. This receptor complex also phosphorylates STAT3 homodimers.

    Drugs: Interferon beta-1a
    Enzymes: Signal transducer and activator of transcription 3, Signal transducer and activator of transcription 2
  10. Pathway

    Triflusal Action Pathway (new)

    smpdb.ca/view/SMP0126547
    Drug action

    Due to the anticoagulant and antiplatelet nature, herbs and supplements with similar activity should be avoided such as garlic, ginger, bilberry, danshen, piracetam and ginkgo biloba. … Triflusal is administered orally and acts as an antithrombotic anticoagulant that irreversibly inhibits cyclooxygenase-1(COX-1) also known as prostaglandin g/h synthase 1.

    Drugs: Adenosine phosphate · ATP · Magnesium cation · Zinc · Cyclic adenosine monophosphate · Mesoheme +2 more
    Enzymes: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A