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Displaying results 111 - 120 of 382 in total
  1. Drug

    Hemoximer

    go.drugbank.com/drugs/DB17600
    Investigational

    Hemoximer is a modified version of hemoglobin that undergoes pyridoxylation, for the purpose of lowering the oxygen affinity, and coupling with polyoxyethylene (POE), to increase its molecular weight.

  2. Target

    Potassium channel subfamily K member 6

    go.drugbank.com/bio_entities/BE0000680
    TargetHumans

    K(+) channel that conducts outward rectifying currents at the membranes of the endolysosomal system (PubMed:10887187, PubMed:28381826, PubMed:40343992, PubMed:41617707). Active in lysosomes where it regulates lysosome numbers and size (P...

    Synonyms: TWIK-originated similarity sequence, Inward rectifying potassium channel protein TWIK-2
  3. Drug

    Affitope AD01

    go.drugbank.com/drugs/DB06086
    Investigational

    AD01 is a short peptide (7 amino acids in length) that induces Aß-targeting antibodies, therefore lowering Aß aggregates.

  4. Drug

    Evolocumab

    go.drugbank.com/drugs/DB09303
    ApprovedInvestigational

    It is a subcutaneous injection approved by the FDA for individuals on maximum statin therapy who still require additional LDL-cholesterol lowering.

  5. Drug

    Lovastatin

    go.drugbank.com/drugs/DB00227
    ApprovedInvestigational

    Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of _Aspergillus terreus_.

  6. Target

    Coagulation factor X

    go.drugbank.com/bio_entities/BE0000216
    TargetEnzymeHumans

    Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting (PubMed:22409427, PubMed:39880037). Factor Xa activates pro-inflammatory s...

    Synonyms: Stuart-Prower factor
  7. Drug

    Flibanserin

    go.drugbank.com/drugs/DB04908
    Approved

    Flibanserin's mechanism of action is attributed to its high affinity for 5-HTA1 and 5-HTA2 receptors, displaying agonist activity on 5-HTA1 and antagonist on 5-HTA2, resulting in lowering of serotonin

  8. Drug

    Linerixibat

    go.drugbank.com/drugs/DB11729
    ApprovedInvestigational

    Linerixibat is a first-in-class and small-molecule inhibitor of the ileal bile acid transporter (IBAT). On March 19, 2026, linerixibat was approved by the FDA for the treatment of cholestatic pruritus in patients with primary biliary cho...

  9. Drug

    Omeprazole

    go.drugbank.com/drugs/DB00338
    ApprovedInvestigationalVet approved

    Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases cha...

    International brands: ProcelacMixtures: INHIBITRON TWIT, INHIBITRON TWIT 40
  10. Drug

    Sodium hydroxide

    go.drugbank.com/drugs/DB11151
    Approved

    Sodium hydroxide is also known as lye or soda , or caustic soda . At room temperature, sodium hydroxide is a white crystalline odorless solid that absorbs moisture from the air. It is a synthetically manufactured substance. When dissolve...

    Mixtures: NUTRIFLEX PERI IN 2000ML TWIN-FLEX, NUTRIFLEX PLUS IN 1000ML TWIN FLEX