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Retifanlimab
go.drugbank.com/drugs/DB15766ApprovedInvestigationaldeath-ligand 2 (PD-L2). … Retifanlimab is a humanized IgG4 kappa monoclonal antibody that binds to the programmed death receptor-1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitorsSynonyms: Anti-PD-1 monoclonal antibody MGA012Propofol
go.drugbank.com/drugs/DB00818ApprovedInvestigationalVet approvedPropofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medic...
Categories: P-glycoprotein inducers, Cytochrome P-450 SubstratesProducts: PROPOFOL-PF %1 200 MG/20 ML I.V. ENJEKSİYONLUK/İNFÜZYONLUK EMÜLSİYON, 5 ADETMetoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigationalDiabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: PP-METOCLOPRAMIDE TABLETCarbamazepine
go.drugbank.com/drugs/DB00564ApprovedInvestigationalCarbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965. Aside from the above uses, ...
Categories: P-glycoprotein inducers, P-glycoprotein substratesProducts: CARBAMAZEPIN 200 1A PHFormoterol
go.drugbank.com/drugs/DB00983ApprovedInvestigationalFormoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racem...
Mixtures: SYMBICORT PI 80/4.5UG120ED, SYMBICORT PI 80/4.5UG120EDCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesIbuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigationalIbuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in ...
Mixtures: Advil PM, Advil PMCategories: P-glycoprotein inhibitors, P-glycoprotein substratesCaloric Restriction
go.drugbank.com/conditions/DBCOND0006244Allantoin
go.drugbank.com/drugs/DB11100ApprovedInvestigationalAllantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, th...
Products: Dr Young 2p Blemish Base SPF35 PA, Young 2P Pearl Brightening Balm SPF35 PAToripalimab
go.drugbank.com/drugs/DB15043ApprovedInvestigationalOne mechanism by which this occurs is through the overexpression of programmed cell death ligand (PD-L1)[A261506] - the binding of PD-L1 (and PD-L2) to its target receptor (PD-1) results in the inhibition … [L48681] Toripalimab is a selective, recombinant, humanized IgG4 monoclonal antibody targeted against the PD-1 receptor.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsTilmicosin
go.drugbank.com/drugs/DB11471InvestigationalVet approvedTilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia haemolytica.
Categories: P-glycoprotein substratesProducts: PF TILMICOSIN PREMIX 20% W/W POWDER